From Classical Bacterins to Recombinant Vaccines: Critical Aspects of the Immune Response in Ruminants.

Juliana Loria, Cynthia Baldwin, Walter Lilenbaum

Abstract readReview

In one paragraph

Review in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Juliana LoriaLaboratory of Veterinary Bacteriology, Biomedical Institute, Federal Fluminense University, 101 Prof. Hernani Melo Street, Niteroi 24210-130, RJ, Brazil.

Cynthia BaldwinDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.

Walter LilenbaumLaboratory of Veterinary Bacteriology, Biomedical Institute, Federal Fluminense University, 101 Prof. Hernani Melo Street, Niteroi 24210-130, RJ, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptospirosis is a neglected zoonosis causing significant economic losses in livestock, primarily through Bovine Genital Leptospirosis (BGL). While current vaccines prevent clinical disease, they typically fail to provide sterilizing immunity against adapted strains. This allows

Indexed as

chronic diseaseleptospirosissterilizing immunityTh1 immune responseγδ T cells

Identifiers

PMID42075186

DOI10.3390/microorganisms14040790

PMCPMC13118536

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.