Evidence map›Paper›PMID 42075073›Full record

ArticleNutrients2026

Fermentation Enhances Antioxidant, Antiplatelet, and Anti-Inflammatory Properties of Oat- and Soy-Derived Dairy Alternatives.

Nikolaos Koutis, Georgios Liepouris, Ilianna Moysidou, Lydia Vogiatzaki, Katie Shiels, Sushanta Kumar Saha, Anna Ofrydopoulou, Alexandros Tsoupras

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nikolaos KoutisHephaestus Laboratory, School of Chemistry, Faculty of Sciences, Democritus University of Thrace, 65404 Kavala, Greece.ORCID 0009-0005-0973-2368
Georgios LiepourisHephaestus Laboratory, School of Chemistry, Faculty of Sciences, Democritus University of Thrace, 65404 Kavala, Greece.
Ilianna MoysidouHephaestus Laboratory, School of Chemistry, Faculty of Sciences, Democritus University of Thrace, 65404 Kavala, Greece.
Lydia VogiatzakiHephaestus Laboratory, School of Chemistry, Faculty of Sciences, Democritus University of Thrace, 65404 Kavala, Greece.
Katie ShielsCentre for Applied Bioscience Research, Technological University of the Shannon: Midlands Midwest, Moylish Park, V94 E8YF Limerick, Ireland.ORCID 0000-0003-1603-8882
Sushanta Kumar SahaCentre for Applied Bioscience Research, Technological University of the Shannon: Midlands Midwest, Moylish Park, V94 E8YF Limerick, Ireland.ORCID 0000-0002-3981-8833
Anna OfrydopoulouHephaestus Laboratory, School of Chemistry, Faculty of Sciences, Democritus University of Thrace, 65404 Kavala, Greece.ORCID 0000-0003-3925-6284
Alexandros TsouprasHephaestus Laboratory, School of Chemistry, Faculty of Sciences, Democritus University of Thrace, 65404 Kavala, Greece.ORCID 0000-0002-0837-9778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increasing demand for plant-based dairy alternatives has stimulated interest in their potential health-promoting properties, particularly when combined with fermentation processes that may enhance the bio-efficacy and bioavailability of bioactive compounds.

methodsThe present study investigated the impact of fermentation on the antioxidant, antiplatelet, and anti-inflammatory activities of oat- and soy-based dairy alternatives. Total lipids were extracted and fractionated into lipophilic and amphiphilic lipid fractions, which were subsequently evaluated for antioxidant capacity using 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and ferric reducing antioxidant power (FRAP) assays, as well as for their inhibitory activity against platelet aggregation induced by platelet-activating factor (PAF) or by ADP.

resultsFermentation significantly enhanced the biological activity of the tested products, with fermented samples exhibiting lower IC

conclusionsThese findings suggest that fermentation can substantially improve the biofunctional profile of plant-based dairy alternatives and highlight fermented oat- and soy-based products as promising dietary sources of bioactive polar lipids with potential cardioprotective properties.

Indexed as

Anti-Inflammatory AgentsAntioxidantsAvenaFermentationGlycine maxPlatelet Aggregation InhibitorsHumansPlatelet AggregationAnti-Inflammatory AgentsAntioxidantsPlatelet Aggregation Inhibitorsanti-inflammatoryantioxidantcarotenoidsdairy alternativesoatPAFphenolicspolar lipidsPUFAsoy

Identifiers

PMID42075073
PMCPMC13119166

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.