Evidence map›Paper›PMID 42075000›Full record

ArticleNutrients2026

Deficiency and Excess of Folic Acid Intake Promote Colorectal Carcinogenesis in AOM/DSS-Treated Mice: Roles in Uracil Misincorporation and DNA Methylation.

Qinghan Ren, Yunfei Ma, Zhenshu Li, Qi Wu, Tongtong Li, Xin He, Wen Li, Yongjie Chen, Fei Ma, Jing Yan and 1 more

Abstract read
In one paragraph

Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qinghan RenDepartment of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0009-0001-0109-2256
Yunfei MaDepartment of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0009-0003-2286-1557
Zhenshu LiDepartment of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0002-0117-653X
Qi WuDepartment of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0009-0004-6108-644X
Tongtong LiDepartment of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0002-7958-2562
Xin HeDepartment of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0009-0002-0813-4786
Wen LiDepartment of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0002-9268-538X
Yongjie ChenDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0002-2559-498X
Fei MaDepartment of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0002-9742-4920
Jing YanKey Laboratory of Prevention and Control of Major Diseases in the Population, Ministry of Education, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0003-0203-8451
Guowei HuangDepartment of Nutrition and Food Science, School of Public Health, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0002-0346-6303

Funding

National Natural Science Foundation of China 82373571
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CarcinogenesisColorectal NeoplasmsDNA MethylationFolic AcidFolic Acid DeficiencyUracilAnimalsAzoxymethaneCell ProliferationDextran SulfateMaleMiceMice, Inbred BALB CThymidylate SynthaseAzoxymethaneDextran SulfateFolic AcidThymidylate SynthaseUracilcolorectal cancerdeficiencyDNA methylationexcessfolic acidmouseuracil misincorporation

Identifiers

PMID42075000
PMCPMC13118905

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.