Evidence map›Paper›PMID 42074831›Full record

ArticleJournal of clinical medicine2026

Efficacy of Second-Line Advanced Therapy in Patients with Crohn's Disease After Failure of a First Anti-TNF: A Descriptive Analysis.

Corina Meianu, Carmen Monica Preda, Mircea Diculescu, Doina Istratescu, Anca Trifan, Alina Tantau, Ana Maria Singeap, Cristian George Tieranu, Horia Minea, Ana-Maria Buzuleac and 7 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Corina MeianuUMF "Carol Davila", Gastroenterology & Hepatology Department, 020021 Bucharest, Romania.
Carmen Monica PredaUMF "Carol Davila", Gastroenterology & Hepatology Department, 020021 Bucharest, Romania.
Mircea DiculescuUMF "Carol Davila", Gastroenterology & Hepatology Department, 020021 Bucharest, Romania.
Doina IstratescuGastroenterology & Hepatology Department, Clinic Fundeni Institute, 022328 Bucharest, Romania.
Anca TrifanDepartment of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0001-9144-5520
Alina TantauCluj CF University Hospital, UMF "Iuliu Hatieganu" Cluj, 400347 Cluj, Romania.ORCID 0000-0001-5975-0779
Ana Maria SingeapDepartment of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0001-5621-548X
Cristian George TieranuUMF "Carol Davila", Gastroenterology & Hepatology Department, 020021 Bucharest, Romania.ORCID 0000-0001-5348-0341
Horia MineaDepartment of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-7736-8140
Ana-Maria BuzuleacDepartment of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.
Lucian NegreanuUMF "Carol Davila", Gastroenterology & Hepatology Department, 020021 Bucharest, Romania.ORCID 0000-0003-3042-0754
Remus PopescuInternal Medicine Department, Emergency Universitary Hospital, 050471 Bucharest, Romania.
Andreea BotaGastroenterology & Hepatology Department, Elias Emergency Hospital, 011461 Bucharest, Romania.ORCID 0000-0001-7460-3830
Tudor StroieUMF "Carol Davila", Gastroenterology & Hepatology Department, 020021 Bucharest, Romania.
Letitia TuguiGastroenterology & Hepatology Department, Clinic Fundeni Institute, 022328 Bucharest, Romania.
Andreea-Maria CazimirovitzGastroenterology & Hepatology Department, Elias Emergency Hospital, 011461 Bucharest, Romania.
Cosmin Alexandru CioraUMF "Carol Davila", Gastroenterology & Hepatology Department, 020021 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adalimumabbiologic therapyCrohn’s diseaseinfliximabreal-world datasecond-line therapytreatment sequencingustekinumabvedolizumab

Identifiers

PMID42074831
PMCPMC13116573

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.