ArticleGenes2026
Multi-Omics Mendelian Randomization and Clinical Validation Implicate NLRP6 as a Candidate Autophagy-Related Gene in Systemic Lupus Erythematosus.
Daan Nie, Jianguo Yin, Wei Tu, Kecheng Huang, Jing Wan, Yikai Yu, Bei Wang, Yu Chen, Shengyan Lin, Zhipeng Zeng
Abstract read
In one paragraphArticle in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Daan NieDepartment of Cardiology, Hunan University of Medicine General Hospital, Huaihua 418000, China.ORCID 0000-0002-2808-650X Jianguo YinDepartment of Cardiology, Hunan University of Medicine General Hospital, Huaihua 418000, China.
Wei TuDepartment of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Kecheng HuangDepartment of Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Jing WanDepartment of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Yikai YuDepartment of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Bei WangDepartment of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Yu ChenDepartment of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Shengyan LinDepartment of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0003-4035-4666 Zhipeng ZengDepartment of Rheumatology and Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0009-0006-4180-3434 Funding
Hunan Provincial Natural Science Foundation of China 2025JJ70444National Natural Science Foundation of China 82000422
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
AutophagyLupus Erythematosus, SystemicDNA MethylationFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansMendelian Randomization AnalysisMultiomicsPolymorphism, Single NucleotideQuantitative Trait Lociautophagymendelian randomization analysismulti-OmicsNLRP6quantitative trait locisystemic lupus erythematosus
Identifiers
PMID42074584
PMCPMC13115566
What OpenQuestion holds
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LicenceCC BY
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