ArticleInternational journal of molecular sciences2026
The Preliminary Study for the Trial of Using Selected miRNAs for the Laboratory Diagnosis of Colorectal Cancer.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC) is the second most common cancer in Europe. There is a need to explore and validate new blood-based tumor markers to improve the selection of patients who are likely to benefit from an early, non-invasive diagnosis of CRC. The purpose of this report is to present the test protocol and its verification. The study is planned in four phases. The first trial phase involves collecting material, consisting of healthy tissue, diseased tissue, and plasma, from 120 CRC patients over 50 years old during surgery. This phase also involves identifying microRNAs (miRNAs) and comparing their expressed levels in colorectal cancer cells with those in healthy tissue taken from a standard resection margin. We detected measurable levels of miRNAs in tissue samples taken from patients, confirming that the material was correctly removed for testing. Statistically significant differences were obtained between healthy and cancerous tissue for selected miRNAs. Some of the selected miRNAs have higher expression levels in CRC tissue and could be potential candidate biomarkers for laboratory-based colorectal cancer diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.