Evidence map›Paper›PMID 42074322›Full record

ArticleInternational journal of molecular sciences2026

Glomerulus-Specific Inhomogeneity of the Basal Activity Map in the Olfactory Bulb.

Stefan Fink, Natalie Fomin-Thunemann, Farzin Kamari, Yury Kovalchuk, Olga Garaschuk

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefan FinkInstitute of Physiology, Department of Neurophysiology, Eberhard Karls University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0002-7938-9869
Natalie Fomin-ThunemannInstitute of Physiology, Department of Neurophysiology, Eberhard Karls University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0003-0449-4645
Farzin KamariInstitute of Physiology, Department of Neurophysiology, Eberhard Karls University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0003-4774-5168
Yury KovalchukInstitute of Physiology, Department of Neurophysiology, Eberhard Karls University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0001-7457-7097
Olga GaraschukInstitute of Physiology, Department of Neurophysiology, Eberhard Karls University of Tübingen, 72074 Tübingen, Germany.ORCID 0000-0001-7400-5654

Funding

DFG GA 654/16-1 and GA 654/18-1 to O.G
6 · The paper itself

Abstract

Glomeruli are signal-processing units of the olfactory bulb (OB) that play a key role in many OB computations, including contrast enhancement, gain control, and odorant-selective habituation. In awake mice, we unveil an extremely stable, inhomogeneous map of basal glomerulus-specific activity that serves as the background against which olfactory signal processing occurs. This activity is strongly driven by centrifugal cholinergic inputs; endogenous and airflow-evoked spiking of olfactory sensory neurons; and, to a minor extent, by the odor environment. Moreover, it is brain-state dependent and suppressed under various forms of anesthesia, and is therefore likely attenuated during sleep. These results reveal an important layer in the OB signal-processing network, likely increasing the system's variance and dynamic range via glomerulus-specific functional inhomogeneity.

Indexed as

Olfactory BulbOlfactory Receptor NeuronsAnimalsMaleMiceMice, Inbred C57BLOdorantsSmellWakefulnessawake recordingsfirst stage of olfactory sensationin vivo calcium imagingolfactory signal processing

Identifiers

PMID42074322
PMCPMC13116878

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.