Evidence map›Paper›PMID 42074256›Full record

ArticleInternational journal of molecular sciences2026

Intermittent Fasting Ameliorates Testicular Damage via Oxidative Stress Modulation in a Genetic Absence Epilepsy Rat Model.

Damla Gökçeoğlu Kayalı, Hatice Maraş, Aybüke Çilingir, Ahmet Anıl Keskin, Çağan Yardımcı, Fatma Beyza Aykurt, Eda Nur Arslan, Bircan Kolbaşı-Erkan, Zarife Nigar Özdemir-Kumral, Ozlem Tugce Cilingir-Kaya

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Damla Gökçeoğlu KayalıDepartment of Histology and Embryology, School of Medicine, Istanbul Atlas University, 34408 Istanbul, Türkiye.ORCID 0000-0003-0674-090X
Hatice MaraşDepartment of Histology and Embryology, School of Medicine, Marmara University, 34854 Istanbul, Türkiye.
Aybüke ÇilingirSchool of Medicine, Marmara University, 34854 Istanbul, Türkiye.
Ahmet Anıl KeskinSchool of Medicine, Marmara University, 34854 Istanbul, Türkiye.ORCID 0009-0002-5859-3972
Çağan YardımcıSchool of Medicine, Marmara University, 34854 Istanbul, Türkiye.ORCID 0009-0006-9712-0448
Fatma Beyza AykurtSchool of Medicine, Marmara University, 34854 Istanbul, Türkiye.
Eda Nur ArslanSchool of Medicine, Marmara University, 34854 Istanbul, Türkiye.ORCID 0009-0002-7376-9403
Bircan Kolbaşı-ErkanDepartment of Histology and Embryology, School of Medicine, Istanbul Medipol University, 34815 Istanbul, Türkiye.ORCID 0000-0001-7933-4262
Zarife Nigar Özdemir-KumralDepartment of Physiology, School of Medicine, Marmara University, 34854 Istanbul, Türkiye.ORCID 0000-0002-9485-0174
Ozlem Tugce Cilingir-KayaDepartment of Histology and Embryology, School of Medicine, Marmara University, 34854 Istanbul, Türkiye.ORCID 0000-0002-2591-9174

Funding

Marmara University Scientific Research Project Unit TDK-2023-11023Scientific and Technological Research Council of Turkey Health Institutes (TÜSEB) 38924)
6 · The paper itself

Abstract

Epilepsy is associated with impaired reproductive function and testicular pathologies. Intermittent fasting (IF) is a nonpharmacological metabolic intervention with anti-inflammatory and antioxidant effects. This study investigated the protective effects of IF on testicular damage in a genetic absence epilepsy rat model (GAERS), focusing on histomorphology, oxidative stress parameters, and hormonal profiles. Testicular tissues from Wistar control (WC), Wistar + IF (WIF), GAERS control (GC), and GAERS + IF (GIF) groups (total

Indexed as

Epilepsy, AbsenceIntermittent FastingOxidative StressTestisAnimalsApoptosisCaspase 3Disease Models, AnimalMaleRatsRats, WistarTestosteroneCaspase 3Testosteronecaspase 3DAZL proteinepilepsyintermittent fastingoxidative stressPIWI proteinstestis

Identifiers

PMID42074256
PMCPMC13115940

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.