Evidence map›Paper›PMID 42074245›Full record

ArticleInternational journal of molecular sciences2026

Developmental Differences in Circular RNA Expression Between Adult and Fetal Human Salivary Glands Based on Public Total RNA-Sequencing Data.

Zahra A Aldawood, Alawi Habara

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zahra A AldawoodDepartment of Biomedical Dental Science, College of Dentistry, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia.
Alawi HabaraDepartment of Biochemistry, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam 34212, Saudi Arabia.ORCID 0000-0002-5384-8764

Funding

Imam Abdulrahman Bin Faisal University NA
6 · The paper itself

Abstract

Circular RNAs (circRNAs) are stable regulatory RNAs whose developmental patterns in human salivary glands remain poorly defined. Publicly available total RNA-seq data from adult and fetal salivary glands (GSE143702-adult, n = 13; fetal, n = 14) were analyzed to profile the circRNA expression and evaluate developmental-stage differences. Reads were aligned with STAR using chimeric detection, circRNAs were parsed and annotated with CIRCexplorer2, and circRNAs supported by ≥2 back-splice junction reads were retained for quantification. Principal component analysis (PCA) of circRNA expression profiles demonstrated significant (PERMANOVA

Indexed as

FetusGene Expression Regulation, DevelopmentalRNA, CircularSalivary GlandsAdultFemaleGene Expression ProfilingHumansMicroRNAsSequence Analysis, RNAMicroRNAsRNA, Circularadult salivary glandscircRNAfetal salivary glandshuman development of salivary glandsmiRNA

Identifiers

PMID42074245
PMCPMC13116067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.