ArticleInternational journal of molecular sciences2026
Arresting the Activity of Bacterial β-Barrel Pore-Forming Toxins by Cysteine Insertion Mutagenesis in the Homologous Region.
Alexander V Siunov, Bogdan S Melnik, Alexey S Nagel, Zhanna I Andreeva-Kovalevskaya, Natalia V Rudenko, Anna P Karatovskaya, Olesya S Vetrova, Anna V Zamyatina, Fedor A Brovko, Alexander S Solonin
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In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
10 authors.
Alexander V SiunovFSBIS FRC Pushchino Scientific Centre of Biological Research, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, 5 Prospekt Nauki, 142290 Pushchino, Russia.ORCID 0000-0001-5511-6594 Bogdan S MelnikInstitute of Protein Research, Russian Academy of Sciences, 4 Institutskaya Street, 142290 Pushchino, Russia.ORCID 0000-0002-9176-6452 Alexey S NagelFSBIS FRC Pushchino Scientific Centre of Biological Research, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, 5 Prospekt Nauki, 142290 Pushchino, Russia.
Zhanna I Andreeva-KovalevskayaFSBIS FRC Pushchino Scientific Centre of Biological Research, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, 5 Prospekt Nauki, 142290 Pushchino, Russia.
Natalia V RudenkoPushchino Branch, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Prospekt Nauki, 142290 Pushchino, Russia.ORCID 0000-0002-7332-7587 Anna P KaratovskayaPushchino Branch, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Prospekt Nauki, 142290 Pushchino, Russia.
Olesya S VetrovaPushchino Branch, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Prospekt Nauki, 142290 Pushchino, Russia.ORCID 0009-0002-5777-8721 Anna V ZamyatinaPushchino Branch, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Prospekt Nauki, 142290 Pushchino, Russia.
Fedor A BrovkoPushchino Branch, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 6 Prospekt Nauki, 142290 Pushchino, Russia.
Alexander S SoloninFSBIS FRC Pushchino Scientific Centre of Biological Research, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, 5 Prospekt Nauki, 142290 Pushchino, Russia.
Funding
Russian Science Foundation project No. 22-74-10026-P
6 · The paper itselfAbstract
Bacterial β-barrel pore-forming toxins, including
Indexed as
Bacterial ToxinsCysteineHemolysin ProteinsMutagenesis, InsertionalPore Forming Cytotoxic ProteinsAnimalsBacillus cereusHemolysisHumansMiceModels, MolecularStaphylococcus aureusBacterial ToxinsCysteineHemolysin ProteinsPore Forming Cytotoxic Proteinsstaphylococcal alpha-toxinbacterial β-barrel pore-forming toxinsCytK-2disulfide bond formationhemolytic activityHlaHlyIImonoclonal antibodiesmouse model
Identifiers
PMID42074228
PMCPMC13116651
What OpenQuestion holds
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