Evidence map›Paper›PMID 42074205›Full record

ArticleInternational journal of molecular sciences2026

Evaluation of the Anticancer Effects of

Daniel M Tswaledi, Matlou P Mokgotho, Makgwale S Mphahlele, Raymond T Makola, Jean B Ngilirabanga, Bwalya A Witika, Emelinah H Mathe, Stanley S Gololo, Ananias H Kgopa, Leshweni J Shai

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniel M TswalediDepartment of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0002-9960-5565
Matlou P MokgothoDepartment of Physiology, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0003-0779-562X
Makgwale S MphahleleDepartment of Biomedical Sciences, Tshwane University of Technology, Pretoria 0183, South Africa.
Raymond T MakolaDepartment of Biochemistry and Microbiology, University of Limpopo, Sovenga 0727, South Africa.
Jean B NgilirabangaDepartment of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0002-8040-1298
Bwalya A WitikaDepartment of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0002-4034-9368
Emelinah H MatheDepartment of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0003-4946-2874
Stanley S GololoDepartment of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0002-8059-1941
Ananias H KgopaDepartment of Biochemistry and Biotechnology, School of Science and Technology, Sefako Makgatho Health Sciences University, Pretoria 0204, South Africa.ORCID 0000-0003-0063-5156
Leshweni J ShaiDepartment of Biomedical Sciences, Tshwane University of Technology, Pretoria 0183, South Africa.ORCID 0000-0003-4799-7437

Funding

National Research Foundation MND200624535874
6 · The paper itself

Abstract

Although medicinal plants possess vast biological properties, crude medicinal plant extracts often show limited therapeutic efficacy due to poor aqueous solubility, instability, and inadequate bioavailability, which restricts efficient intracellular delivery. As cancer is a genetic disease requiring intracellular and nuclear targeting, improved delivery systems are essential.

Indexed as

Antineoplastic Agents, PhytogenicApoptosisLiposomesPlant ExtractsPlant LeavesAnimalsChlorocebus aethiopsHumansMCF-7 CellsMiceRAW 264.7 CellsSignal TransductionVero CellsAntineoplastic Agents, PhytogenicLiposomesPlant Extractsapoptosiscancercellular metabolic activityliposomesWarburgia salutaris

Identifiers

PMID42074205
PMCPMC13115591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.