Evidence map›Paper›PMID 42074158›Full record

ArticleInternational journal of molecular sciences2026

Early Biohumoral Detection of Acute Kidney Injury After Robotic Renal Surgery and Its Impact on Medium-Term Renal Function.

Raffaele La Mura, Alessio Paladini, Paolo Mangione, Guido Massa, Jessica Pagnotta, Federico Ricci, Matteo Mearini, Giuseppe Giardino, Andrea Vitale, Ettore Mearini and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Raffaele La MuraDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0009-0001-1873-4032
Alessio PaladiniDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0000-0003-2680-3429
Paolo MangioneDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0009-0008-6183-2309
Guido MassaDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.
Jessica PagnottaDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0009-0000-1962-2692
Federico RicciDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0009-0002-5084-5346
Matteo MeariniDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0009-0003-3122-3864
Giuseppe GiardinoDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.
Andrea VitaleDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0009-0002-9567-8780
Ettore MeariniDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0000-0003-1652-2965
Giovanni CochettiDepartment of Medicine and Surgery, Urology Clinic, University of Perugia, 06129 Perugia, Italy.ORCID 0000-0003-3982-2004

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal surgery for localized renal cell carcinoma carries substantial risk of acute kidney injury (AKI) regardless of surgical approach. This prospective study evaluated early biohumoral markers for AKI detection after robotic renal surgery and assessed their prognostic value for 12-month functional outcomes. Adults undergoing robotic renal tumor surgery with a healthy contralateral kidney were enrolled; AKI followed KDIGO 2012 criteria. Biomarkers measured at baseline and 2/24/72 h were serum β2-microglobulin (sβ2) serum IL-6, as well as urinary β2-microglobulin (uβ2), cystatin C (uC), and α2-macroglobulin (uα2M). Kidney function at 12 months was staged according to KDOQI criteria. Among 170 patients (35 radical nephrectomy, RN; 135 partial nephrectomy, PN), 33 developed AKI, more frequently after RN (

Indexed as

Acute Kidney InjuryNephrectomyRobotic Surgical ProceduresAgedalpha-Macroglobulinsbeta 2-MicroglobulinBiomarkersCarcinoma, Renal CellCystatin CFemaleHumansInterleukin-6KidneyKidney NeoplasmsMaleMiddle Agedalpha-Macroglobulinsbeta 2-MicroglobulinBiomarkersCystatin CInterleukin-6acute kidney injurybiomarkerscystatin Cinterleukin-6partial nephrectomyradical nephrectomyrenal cell carcinomarobotic surgeryβ2-microglobulin

Identifiers

PMID42074158
PMCPMC13116045

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.