Evidence map›Paper›PMID 42074148›Full record

ReviewInternational journal of molecular sciences2026

Genetic Risk Factors and Clinical Implications of Glaucoma in the Saudi Population: A Review.

Abdullah Faisal Alotaibi, Lojain Mohammed A Maawadh, Mohammed Naji Obaid Almutairi, Syed Hameed, Rizwan Malik, Khaled K Abu-Amero

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abdullah Faisal AlotaibiGlaucoma Division, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.
Lojain Mohammed A MaawadhCollege of Medicine, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.
Mohammed Naji Obaid AlmutairiCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh 11481, Saudi Arabia.ORCID 0009-0007-8434-3148
Syed HameedResearch Department, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.ORCID 0009-0004-2746-0784
Rizwan MalikResearch Department, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.
Khaled K Abu-AmeroResearch Department, King Khaled Eye Specialist Hospital and Research Center, Riyadh 11462, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most glaucoma genetic data derive from European and East Asian cohorts, leaving high-consanguinity Middle Eastern populations under-characterized. This review synthesizes 33 Saudi-specific genetic studies (2014-2024, >9000 participants) to define a population-level glaucoma genetic architecture that diverges substantially from global models and carries direct precision medicine implications. Three findings distinguish the Saudi landscape. First,

Indexed as

Genetic Predisposition to DiseaseGlaucomaCytochrome P-450 CYP1B1Eye ProteinsGlaucoma, Open-AngleHumansLatent TGF-beta Binding ProteinsMyocilinRisk FactorsSaudi ArabiaCYP1B1 protein, humanCytochrome P-450 CYP1B1Eye ProteinsLatent TGF-beta Binding ProteinsLTBP2 protein, humanMyocilinAPOEconsanguinityCYP1B1geneticsglaucomapersonalized medicinerisk factorsSaudi Arabia

Identifiers

PMID42074148
PMCPMC13116526

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.