Evidence map›Paper›PMID 42074134›Full record

SynthesisInternational journal of molecular sciences2026

Use of Artificial Intelligence in the Interpretation of Electroretinography (ERG) Studies.

Manasi Hegde, Alexander Thomis, Sheetal Shirke

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Manasi HegdeDepartment of Ophthalmology, Townsville University Hospital, 100 Angus Smith Drive, Douglas, Townsville, QLD 4814, Australia.ORCID 0009-0008-0456-7609
Alexander ThomisDepartment of Ophthalmology, Townsville University Hospital, 100 Angus Smith Drive, Douglas, Townsville, QLD 4814, Australia.ORCID 0009-0006-3347-1599
Sheetal ShirkeDepartment of Ophthalmology, Townsville University Hospital, 100 Angus Smith Drive, Douglas, Townsville, QLD 4814, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electroretinograms are an important diagnostic tool to measure retinal electrical activity. However, their interpretation, done by sub-specialised ophthalmologists, can be not only time consuming but also challenging to obtain due to availability. In recent years, studies have investigated the use of artificial intelligence in the analysis of electroretinograms. This systematic review summarises the accuracy of artificial intelligence in interpreting electroretinograms and appraises the studies included. The review comprises primary, peer-reviewed published studies that determined accuracy of artificial intelligence by comparison to an expert ophthalmologist. In the 14 studies retrieved from databases and published between 2006 and 2025, machine learning was the most widely used artificial intelligence, with an accuracy rate between 39.3% and 100%. Overall, the "artificial neural network" machine learning tool was the most accurate. Quality assessment of the studies demonstrated high bias in patient selection but robustness in the methodology for the reference standard, flow and timing. The results revealed potential benefits in the real-world use of artificial intelligence in ophthalmic diagnostic testing; however, the variability in results suggests a requirement for further investigation prior to clinical implementation.

Indexed as

Artificial IntelligenceElectroretinographyRetinaHumansMachine Learningartificial intelligencediagnostic accuracyelectroretinograms

Identifiers

PMID42074134
PMCPMC13115667

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.