Evidence map›Paper›PMID 42073635›Full record

ArticleCancers2026

MDK Activates the PI3K/AKT Axis to Induce AP2A1 Expression and Epithelial-Mesenchymal Transition in Colorectal Cancer.

Tengfei Li, Chengyuan Xu, Yang Guo, Yanyan Xu, Kaiji Chen, Yunsheng Cheng, Kesavamoorthy Gandhervin, Jianming Zhang, Moubin Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tengfei LiDepartment of General Surgery, Yangpu Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai 200082, China.ORCID 0000-0001-9179-5109
Chengyuan XuDepartment of General Surgery, Yangpu Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai 200082, China.
Yang GuoGeneral Surgery, Cancer Center, Department of Colorectal Surgery, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou 310014, China.
Yanyan XuDepartment of General Surgery, Yangpu Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai 200082, China.
Kaiji ChenDepartment of General Surgery, Yangpu Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai 200082, China.
Yunsheng ChengDepartment of General Surgery, Second Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei 230601, China.
Kesavamoorthy GandhervinDepartment of Medicine, The University of Hong Kong, Hong Kong, China.
Jianming ZhangDepartment of Oncology, Pudong Hospital Affiliated to Fudan University, Fudan University School of Medicine, Shanghai 201399, China.
Moubin LinDepartment of General Surgery, Yangpu Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai 200082, China.

Funding

National Natural Science Foundation of China 32370755Research Fund Program of Anhui Medical University 2022xkj044Research Fund Program of Anhui Medical University 2022xkj173Science and Technology Commission of Shanghai Municipality 20Y11908300
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AP2A1colorectal cancerEMTMDKPI3K/AKT

Identifiers

PMID42073635
PMCPMC13114282

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.