Evidence map›Paper›PMID 42073609›Full record

ArticleCancers2026

Heterogeneity of PD-L1 Expression Between the Primary Tumor and Matched Lymph Node Metastases in Head and Neck Squamous Cell Carcinomas.

Moritz Knebel, Gilbert Georg Klamminger, Jan Philipp Kühn, Sandrina Körner, Silke Wemmert, Lukas Alexander Brust, Felix Braun, Sigrun Smola, Mathias Wagner, Martin Ertz and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Moritz KnebelInstitute of Otorhinolaryngology, Saarland University, 66421 Homburg, Germany.ORCID 0009-0001-5996-6657
Gilbert Georg KlammingerDepartment of General and Surgical Pathology, Saarland University Medical Center, 66421 Homburg, Germany.
Jan Philipp KühnInstitute of Otorhinolaryngology, Saarland University, 66421 Homburg, Germany.
Sandrina KörnerInstitute of Otorhinolaryngology, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-6435-2940
Silke WemmertInstitute of Otorhinolaryngology, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-7109-5188
Lukas Alexander BrustInstitute of Otorhinolaryngology, Saarland University, 66421 Homburg, Germany.ORCID 0009-0007-6961-8510
Felix BraunInstitute of Otorhinolaryngology, Saarland University, 66421 Homburg, Germany.
Sigrun SmolaInstitute of Virology, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0003-3289-6545
Mathias WagnerDepartment of General and Surgical Pathology, Saarland University Medical Center, 66421 Homburg, Germany.
Martin ErtzDepartment of General and Surgical Pathology, Saarland University Medical Center, 66421 Homburg, Germany.
Luc G T MorrisDepartment of Surgery, Memorial Sloan Kettering Cancer Center, New York City, NY 10065, USA.ORCID 0000-0002-4417-2280
Bernhard SchickInstitute of Otorhinolaryngology, Saarland University, 66421 Homburg, Germany.
Maximilian LinxweilerInstitute of Otorhinolaryngology, Saarland University, 66421 Homburg, Germany.ORCID 0000-0002-5028-9282

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Else Kröner-Fresenius-Stiftung 2022 EKEA.21NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HNSCCimmunotherapylymph node metastasesPD-L1 expressionspatial heterogeneitytumor microenvironment

Identifiers

PMID42073609
PMCPMC13114373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.