Evidence map›Paper›PMID 42073112›Full record

ReviewChildren (Basel, Switzerland)2026

Surgical Treatment of Tethered Cord Syndrome by Release of Filum Terminalis: A Review.

Marios Lampros, Flavio Giordano, Panagiota Zagorianakou, George A Alexiou, Spyridon Voulgaris

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marios LamprosDepartment of Neurosurgery, School of Medicine, University Hospital of Ioannina, 45500 Ioannina, Greece.
Flavio GiordanoFunctional Neurosurgery and Epilepsy Neurosurgery and Pediatric Neurosurgery Unit Meyer Children's Hospital IRCCS Florence, 50139 Firenze, Italy.ORCID 0000-0002-9006-9225
Panagiota ZagorianakouDepartment of Neurosurgery, School of Medicine, University Hospital of Ioannina, 45500 Ioannina, Greece.
George A AlexiouDepartment of Neurosurgery, School of Medicine, University Hospital of Ioannina, 45500 Ioannina, Greece.ORCID 0000-0003-0257-4481
Spyridon VoulgarisDepartment of Neurosurgery, School of Medicine, University Hospital of Ioannina, 45500 Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tethered cord syndrome (TCS) is a disease caused by pathological fixation of the spinal cord, most commonly due to a thickened filum terminale, postoperative adhesions, or congenital dysraphism. Progressive neurological, urological, and orthopedic manifestations result from chronic cord traction and impaired vascular supply. Surgical detethering remains the standard treatment, with the classic intradural sectioning of the filum terminale being the most widely used technique. Recent developments, however, include minimally invasive tubular and endoscopic approaches, spinal column shortening procedures for recurrent or complex cases, and extradural detethering strategies. Each technique aims to reduce cord tension while minimizing postoperative complications, particularly cerebrospinal fluid leakage and retethering. This review summarizes the anatomical background, pathophysiology, and operative strategies for TCS, highlighting current evidence, technical nuances, and limitations of emerging minimally invasive and alternative approaches.

Indexed as

detetheringfilum terminaletethered cord syndrome

Identifiers

PMID42073112
PMCPMC13114283

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.