Evidence map›Paper›PMID 42072910›Full record

ArticleHealthcare (Basel, Switzerland)2026

Normal-Weight Obesity and an Unfavorable Cardiometabolic Profile: Results from the Study of Workers' Health (ESAT).

Fernando Gomes de Jesus, Alice Pereira Duque, Grazielle Vilas Bôas Huguenin, Mauro Felippe Felix Mediano, Maicon Teixeira de Almeida, Carla Christina Ade Caldas, Silvio Rodrigues Marques-Neto, Luiz Fernando Rodrigues Junior

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Article in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fernando Gomes de JesusDepartment of Physiological Sciences, Biomedical Institute, Federal University of the State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil.
Alice Pereira DuqueDepartment of Physiological Sciences, Biomedical Institute, Federal University of the State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil.
Grazielle Vilas Bôas HugueninEducation and Research Department, National Institute of Cardiology, Rio de Janeiro 22240-006, Brazil.ORCID 0000-0002-0553-4939
Mauro Felippe Felix MedianoEducation and Research Department, National Institute of Cardiology, Rio de Janeiro 22240-006, Brazil.
Maicon Teixeira de AlmeidaPrograma de Pós-Graduação em Ciências da Atividade Física (PPGCAF/UNIVERSO), Universidade Salgado de Oliveira, Niterói 24030-060, Brazil.ORCID 0009-0007-2254-2272
Carla Christina Ade CaldasPrograma de Pós-Graduação em Ciências da Atividade Física (PPGCAF/UNIVERSO), Universidade Salgado de Oliveira, Niterói 24030-060, Brazil.
Silvio Rodrigues Marques-NetoPrograma de Pós-Graduação em Ciências da Atividade Física (PPGCAF/UNIVERSO), Universidade Salgado de Oliveira, Niterói 24030-060, Brazil.ORCID 0000-0001-5742-4646
Luiz Fernando Rodrigues JuniorDepartment of Physiological Sciences, Biomedical Institute, Federal University of the State of Rio de Janeiro, Rio de Janeiro 22290-240, Brazil.ORCID 0000-0001-7007-7431

Funding

Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ). E-26/204.447/2025
6 · The paper itself

Abstract

backgroundNormal-weight obesity (NWO) is a nutritional status in which individuals have a normal body mass index (BMI) with a high percentage of body fat (%BF). However, the impact of elevated %BF on cardiometabolic risk remains unclear. This study aimed to evaluate whether NWO is associated with worse cardiometabolic risk markers and scores.

methodsWe conducted a cross-sectional study using a convenience sample of employees from a public hospital. Participants aged ≥18 years with a BMI between 18.5-24.9 kg/m

resultsOf the 228 eligible participants, 52 met the inclusion criteria (NWNB, N = 29 and NWO, N = 23). Participants with NWO presented worse values of lipid profiles, anthropometric measurements, hemodynamic parameters, and autonomic function indices. After adjustment for age and sex, NWO remained associated with selected cardiometabolic markers, particularly LDL-c, triglycerides, and autonomic indices, whereas body composition findings should be interpreted as confirmatory of the phenotype.

conclusionsIn this cross-sectional secondary analysis, NWO was associated with worse cardiometabolic markers and selected risk scores compared with NWNB. These findings support an unfavorable cardiometabolic profile in individuals with NWO, but do not allow inferences about future cardiometabolic events or causal relationships. Longitudinal studies are needed to clarify its prognostic significance.

Indexed as

autonomic functioncardiometabolic riskcardiovascular riskheart rate variabilitynormal weight obesity

Identifiers

PMID42072910
PMCPMC13116948

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