Evidence map›Paper›PMID 42072719›Full record

ArticleBiomolecules2026

The Effects of Baicalin in Combination with Cefotaxime on the Biofilm and Metabolic Reprogramming of Multidrug-Resistant

Xin Meng, Chao Ning, Xinyu Lu, Mengna Kang, Yuxuan Yang, Zhiyun Yu, Yu Wang, Yantong Sun, Haiyong Guo

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin MengCollege of Life Science, Jilin Normal University, Siping 136000, China.
Chao NingCollege of Life Science, Jilin Normal University, Siping 136000, China.
Xinyu LuCollege of Life Science, Jilin Normal University, Siping 136000, China.
Mengna KangCollege of Life Science, Jilin Normal University, Siping 136000, China.
Yuxuan YangCollege of Life Science, Jilin Normal University, Siping 136000, China.
Zhiyun YuCollege of Life Science, Jilin Normal University, Siping 136000, China.
Yu WangCollege of Life Science, Jilin Normal University, Siping 136000, China.
Yantong SunSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.
Haiyong GuoCollege of Life Science, Jilin Normal University, Siping 136000, China.

Funding

Department of Education of Jilin Province NO.JJKH20261179KJ
6 · The paper itself

Abstract

Baicalin, a natural plant-derived compound, holds promise in addressing clinical bacterial resistance when combined with antibiotics. This study evaluated the antibacterial activity of the combination of baicalin and cefotaxime and explored its mechanism of action on the cell wall and biofilm of multidrug-resistant

Indexed as

Anti-Bacterial AgentsBiofilmsCefotaximeDrug Resistance, Multiple, BacterialFlavonoidsPseudomonas aeruginosaBacterial ProteinsCell WallGene Expression Regulation, BacterialMetabolic ReprogrammingMicrobial Sensitivity TestsMolecular Docking SimulationAnti-Bacterial AgentsBacterial ProteinsbaicalinCefotaximeFlavonoidsbaicalinbiofilmcell wallmetabolismmultidrug-resistant Pseudomonas aeruginosa

Identifiers

PMID42072719
PMCPMC13113927

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.