Evidence map›Paper›PMID 42072704›Full record

ArticleBiomolecules2026

Structure-Activity Relationships, Molecular Mechanisms, and Ecotoxicological Evaluation Underlying Nucleoside-Mediated Antifouling Activity.

Sandra Pereira, Isabel B Oliveira, Andreia Palmeira, Maria V Turkina, Vitor Vasconcelos, Alexandre Campos, Joana R Almeida

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sandra PereiraCIIMAR/CIMAR LA, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, 4450-208 Matosinhos, Portugal.ORCID 0000-0002-7646-4026
Isabel B OliveiraCIIMAR/CIMAR LA, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, 4450-208 Matosinhos, Portugal.
Andreia PalmeiraLaboratory of Organic and Pharmaceutical Chemistry, Department of Chemical Sciences, Faculty of Pharmacy, University of Porto, Rua Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
Maria V TurkinaDepartment of Biomedical and Clinical Sciences, Faculty of Medicine and Clinical Sciences, Linköping University, 581 83 Linköping, Sweden.
Vitor VasconcelosCIIMAR/CIMAR LA, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, 4450-208 Matosinhos, Portugal.ORCID 0000-0003-3585-2417
Alexandre CamposCIIMAR/CIMAR LA, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, 4450-208 Matosinhos, Portugal.ORCID 0000-0003-4621-885X
Joana R AlmeidaCIIMAR/CIMAR LA, Interdisciplinary Centre of Marine and Environmental Research, University of Porto, Terminal de Cruzeiros do Porto de Leixões, 4450-208 Matosinhos, Portugal.ORCID 0000-0001-9356-7265

Funding

Fundação para a Ciência e a Tecnologia 17414 (COMPETE2030-FEDER-01194000)Fundação para a Ciência e a Tecnologia 2023.16744.ICDT, nr 17136 (COMPETE2030-FEDER-00853900)Fundação para a Ciência e a Tecnologia LA/P/0101/2020Fundação para a Ciência e a Tecnologia UID/04423/2025NORTE2030 NORTE2030-FEDER-01796500NORTE2030 NORTE2030-FEDER-01799200Plano de Recuperação e Resiliência UID/PRR/04423/2025
6 · The paper itself

Abstract

Marine biofouling remains a major challenge for maritime industries, affecting submerged structures and vessels worldwide. The long-standing reliance on biocidal coatings, together with their documented environmental impacts, has led to increasingly restrictive regulations and an urgent demand for environmentally compatible antifouling (AF) solutions. This study evaluates the AF potential and toxicological profile of two nucleoside analogues, hypoxanthine arabinoside (

Indexed as

BiofoulingInosineNucleosidesAcetylcholinesteraseAnimalsCyanobacteriaEcotoxicologyMolecular Docking SimulationMonophenol MonooxygenaseMytilusStructure-Activity RelationshipAcetylcholinesteraseInosineMonophenol MonooxygenaseNucleosides2′-deoxyinosineantifouling alternativesbio-based solutionshypoxanthine arabinosidenucleosides

Identifiers

PMID42072704
PMCPMC13114020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.