Evidence map›Paper›PMID 42072666›Full record

ArticleBiomolecules2026

Analysis of Circulating and Urinary Levels of hsa-miRNA-770-5p in Diabetic Nephropathy.

Dimitar Nikolov, Georgi Nikolov, Mariela Geneva-Popova, Stanislava Popova-Belova, Mladen Naydenov, Mari Georgieva Karusheva

Abstract read
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Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Dimitar NikolovSecond Department of Internal Diseases, Faculty of Medicine, Clinic of Nephrology, University Hospital "St. George", Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.
Georgi NikolovSecond Department of Internal Diseases, Faculty of Medicine, Clinic of Nephrology, University Hospital "St. George", Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0003-1619-7066
Mariela Geneva-PopovaDepartment of Propedeutics of Internal Diseases "Prof Anton Mitov", Faculty of Medicine, Clinic of Rheumatology, University Hospital "St. George", Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0002-7655-3846
Stanislava Popova-BelovaDepartment of Propedeutics of Internal Diseases "Prof Anton Mitov", Faculty of Medicine, Clinic of Rheumatology, University Hospital "St. George", Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.
Mladen NaydenovDepartment of Human Anatomy and Physiology, Faculty of Biology, University of Plovdiv, 4000 Plovdiv, Bulgaria.
Mari Georgieva KarushevaDepartment of Propedeutics of Internal Diseases "Prof Anton Mitov", Faculty of Medicine, Clinic of Rheumatology, University Hospital "St. George", Medical University-Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0009-0001-2755-1991

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic nephropathy (DN), also referred to as diabetic kidney disease, represents one of the most common microvascular complications of type 2 diabetes mellitus (T2DM) and remains a leading cause of end-stage renal disease worldwide. Conventional clinical markers, including albuminuria and estimated glomerular filtration rate (eGFR), are widely used for diagnosis and staging but may have limited sensitivity for detecting early renal injury and predicting disease progression. In recent years, circulating

objectiveThe present study aimed to evaluate serum and urinary levels of

methodsA total of 257 participants were included and divided into four groups: healthy controls, patients with T2DM without nephropathy, patients with T2DM and DN in CKD stages I-II, and patients with DN undergoing maintenance hemodialysis (MHD). Serum and urinary levels of

resultsSerum levels of

conclusions

Indexed as

Diabetes Mellitus, Type 2Diabetic NephropathiesMicroRNAsAgedBiomarkersCase-Control StudiesFemaleGlomerular Filtration RateHumansMaleMiddle AgedROC CurveBiomarkersMicroRNAsMIRN-770 microRNA, humanbiomarkerdiabetic nephropathymiRNA-770-5pserum miRNAtype 2 diabetes mellitusurinary miRNA levels

Identifiers

PMID42072666
PMCPMC13113390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.