Evidence map›Paper›PMID 42072265›Full record

ArticleBioengineering (Basel, Switzerland)2026

Automated Aortic Quantification Based on Artificial Intelligence: Validation Using Contrast-Enhanced and Non-Contrast CT Scans from the Same Session.

Jia-Sheng Hong, Yun-Hsuan Tzeng, Kuan-Ting Wu, Shih-Yu Huang, Ting-Wei Wang, Guan-Yu Li, Chun-Yi Lin, Ho-Ren Liu, Hai-Neng Fu, Yung-Tsai Lee and 2 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jia-Sheng HongInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0001-8066-8841
Yun-Hsuan TzengHealth Management Center, Cheng Hsin General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-8077-0261
Kuan-Ting WuInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Shih-Yu HuangInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Ting-Wei WangInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0001-7697-6024
Guan-Yu LiInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Chun-Yi LinInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0002-3034-0044
Ho-Ren LiuHealth Management Center, Cheng Hsin General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-0097-2032
Hai-Neng FuHeart Center, Cheng Hsin General Hospital, Taipei 112, Taiwan.
Yung-Tsai LeeHeart Center, Cheng Hsin General Hospital, Taipei 112, Taiwan.ORCID 0000-0002-3928-0164
Wei-Hsian YinSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Yu-Te WuInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0002-6942-0340

Funding

Cheng Hsin General Hospital CY11102, CY113-CY11201-01, CY113-CY11201-02, and CY113-CY11201-03National Yang Ming Chiao Tung University CY11102, CY113-CY11201-01, CY113-CY11201-02, and CY113-CY11201-03University System of Taiwan 115W084700
6 · The paper itself

Abstract

Early detection of aortic dilatation is clinically important for preventing progression to serious aortic disease and enabling timely intervention. We aimed to develop an AI method for quantifying the aorta in both contrast-enhanced and non-contrast CT scans, assisting early detection of aortic dilation. A total of 190 patient cases were analyzed, each having paired contrast-enhanced and non-contrast CT scans acquired in the same session, resulting in 380 scans. Our approach, based on open-source tools, demonstrated strong agreement with manual annotations, particularly in the ascending aorta. For contrast-enhanced CT, the AI achieved a correlation coefficient of 0.987 and intraclass correlation coefficient (ICC) of 0.986; for non-contrast CT, both were 0.945. Compared with clinical records, the sensitivity of AI detection was 97% for contrast-enhanced CT and 94% for non-contrast CT. This AI-based workflow enables highly sensitive automated aortic quantification in both contrast-enhanced and non-contrast CT scans, supporting broader clinical applicability across different imaging conditions.

Indexed as

3D Sliceraortic dilationartificial intelligenceautomated aortic quantificationcomputed tomographycontrast-enhanced CTnon-contrast CTopen-source workflowTotalSegmentator

Identifiers

PMID42072265
PMCPMC13113725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.