Evidence map›Paper›PMID 42072212›Full record

ArticleBioengineering (Basel, Switzerland)2026

Ultrasound-Guided Targeted Injection to the Anterior Labral-Ligamentous Complex of the Shoulder: A Cadaveric Feasibility Study for Regenerative Therapy.

Sang-Hyun Kim, U-Young Lee, Yonghyun Yoon, Jihyo Hwang, Jungyoun Kim, Yoonju Na, Seungbeom Kim, King Hei Stanley Lam, Jeimylo C de Castro, Teinny Suryadi and 1 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sang-Hyun KimCollege of Korean Medicine, Woosuk University, 443, Samnye-ro, Samnye-eup, Wanju-gun, Jeonju 55338, Republic of Korea.ORCID 0000-0001-9692-4838
U-Young LeeDepartment of Anatomy, Catholic Institute for Applied Anatomy, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.ORCID 0000-0002-8990-1213
Yonghyun YoonDepartment of Orthopaedic Surgery, Gangnam Sacred Heart Hospital, Hallym University College of Medicine, 1 Singil-ro, Yeongdeungpo-gu, Seoul 07441, Republic of Korea.ORCID 0000-0001-8746-3718
Jihyo HwangDepartment of Orthopaedic Surgery, Gangnam Sacred Heart Hospital, Hallym University College of Medicine, 1 Singil-ro, Yeongdeungpo-gu, Seoul 07441, Republic of Korea.ORCID 0000-0002-9141-9856
Jungyoun KimDepartment of Orthopaedic Surgery, Gangnam Sacred Heart Hospital, Hallym University College of Medicine, 1 Singil-ro, Yeongdeungpo-gu, Seoul 07441, Republic of Korea.
Yoonju NaDepartment of Physical Medicine and Rehabilitation, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Republic of Korea.
Seungbeom KimInternational Academy of Regenerative Medicine, Inha-ro 489beon-gil, Namdong-gu, Incheon 21574, Republic of Korea.
King Hei Stanley LamBoard of Clinical Research, The International Association of Musculoskeletal Medicine, Kowloon, Hong Kong.ORCID 0000-0003-1392-829X
Jeimylo C de CastroSMARTMD Center for Non-Surgical Pain Interventions, Makati 1205, Philippines.
Teinny SuryadiBoard of Clinical Research, The International Association of Musculoskeletal Medicine, Kowloon, Hong Kong.ORCID 0009-0000-6722-0268
Anwar SuhaimiBoard of Clinical Research, The International Association of Musculoskeletal Medicine, Kowloon, Hong Kong.ORCID 0000-0001-5795-0988

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anterior labral-ligamentous complex (ALLC), formed by the integration of the anterior inferior glenohumeral ligament and anterior glenoid labrum, plays a critical role in shoulder stability and represents a potential target for regenerative injection therapy. However, precise ultrasound-guided targeting of this capsular-labral interface has not been anatomically validated. This feasibility cadaveric study evaluated the accuracy of ultrasound-guided in-plane injection directed at the ALLC at its glenoid attachment. A fresh-frozen human cadaver specimen was examined in the supine position with the shoulder in external rotation. Stepwise lateral-to-medial and cranial-to-caudal ultrasound scanning was performed to localize the ALLC. A 23-gauge needle was advanced in a cranial-to-caudal in-plane trajectory, and 1-2 mL of red filler was injected into the capsular-labral interface. Subsequent layer-by-layer dissection was conducted to assess injectate localization. In both shoulders (2/2), red filler was confined within the ALLC without extra-capsular leakage, diffuse intra-articular pooling, or neurovascular staining. These findings demonstrate the anatomical feasibility of ultrasound-guided targeted delivery to the anterior capsular-labral complex. This proof-of-concept study provides foundational anatomical validation for the development of regenerative injection protocols directed at the shoulder capsular-labral enthesis.

Indexed as

anterior labral–ligamentous complexcadaveric validationcapsulolabral interfacefrozen shoulderinferior glenohumeral ligamentregenerative injection therapyshoulder instabilityultrasound-guided injection

Identifiers

PMID42072212
PMCPMC13113739

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.