Evidence map›Paper›PMID 42072205›Full record

ArticleBioengineering (Basel, Switzerland)2026

Ex Vivo Human Foreskin Tissue Circumcision via High-Frequency Electric Welding.

Xin Chen, Cai-Hui Zhu, Zhong-Zhen Hu, Cheng Liu, Ze-Wen Dong, Jian Qiu, Hui Zhao, Yang Li, Kai Fang, Si-Min Li and 5 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xin ChenCollege of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.ORCID 0009-0002-7197-1683
Cai-Hui ZhuCollege of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.
Zhong-Zhen HuCollege of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.
Cheng LiuCollege of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.
Ze-Wen DongCollege of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.
Jian QiuCollege of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.
Hui ZhaoCollege of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.ORCID 0000-0003-2384-1606
Yang LiDepartment of Urology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gong-Wei Road, Hui-Nan Town, Pudong, Shanghai 201399, China.
Kai FangDepartment of Urology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gong-Wei Road, Hui-Nan Town, Pudong, Shanghai 201399, China.
Si-Min LiDepartment of Urology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gong-Wei Road, Hui-Nan Town, Pudong, Shanghai 201399, China.
Jia-Kuan LiuDepartment of Urology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gong-Wei Road, Hui-Nan Town, Pudong, Shanghai 201399, China.
Dong LiuDepartment of Urology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gong-Wei Road, Hui-Nan Town, Pudong, Shanghai 201399, China.
Sheng-Jie LiangDepartment of Urology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gong-Wei Road, Hui-Nan Town, Pudong, Shanghai 201399, China.
Ke-Fu LiuCollege of Intelligent Robotics and Advanced Manufacturing, Fudan University, Shanghai 200433, China.ORCID 0000-0001-8249-2800
Chu-Hong ChenDepartment of Urology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gong-Wei Road, Hui-Nan Town, Pudong, Shanghai 201399, China.ORCID 0009-0002-6564-5523

Funding

Specialty Feature Construction Project of Pudong Health and Family Planning Commission of Shanghai PWZzb2022-28
6 · The paper itself

Abstract

backgroundDespite the clinical significance of circumcision, traditional suturing is frequently compromised by intraoperative bleeding and lengthy recovery periods. While high-frequency electric welding (HFEW) presents a compelling alternative, its utility in foreskin removal procedures remains unexplored.

methodsEmploying freshly excised human foreskin tissues, this study simulated the circumcision procedure to benchmark HFEW against standard suturing techniques. Critical performance metrics, encompassing tensile integrity, thermal injury scope, and operative efficiency, were rigorously quantified.

resultsHFEW demonstrated exceptional time efficiency, averaging 2.01 ± 0.9 min-a 77.02% reduction relative to conventional suturing (

conclusionsAlthough HFEW yields comparatively lower tensile strength, its remarkable operational efficiency positions it as a viable technical innovation for circumcision. These preliminary findings support the pursuit of further in vivo investigations to confirm its clinical applicability.

Indexed as

heat damage analysishigh frequency electric weldingstress testsurgical time

Identifiers

PMID42072205
PMCPMC13113146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.