Evidence map›Paper›PMID 42072134›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Oxidative Stress and Antioxidant Defense During Liver Regeneration After Acetaminophen Toxicity: The Preventive Potential of the Microalga

Halyna P Kopylchuk, Ivanna M Nykolaichuk, Mariia S Ursatyi, Larysa M Cheban, Oleksii Skorokhod, Oksana M Voloshchuk

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Protective effects ofRedox report : communications in free radical research · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Halyna P KopylchukEducational and Scientific Institute of Biology, Chemistry and Natural Resources, Yuriy Fedkovych Chernivtsi National University, 58012 Chernivtsi, Ukraine.
Ivanna M NykolaichukEducational and Scientific Institute of Biology, Chemistry and Natural Resources, Yuriy Fedkovych Chernivtsi National University, 58012 Chernivtsi, Ukraine.
Mariia S UrsatyiEducational and Scientific Institute of Biology, Chemistry and Natural Resources, Yuriy Fedkovych Chernivtsi National University, 58012 Chernivtsi, Ukraine.
Larysa M ChebanEducational and Scientific Institute of Biology, Chemistry and Natural Resources, Yuriy Fedkovych Chernivtsi National University, 58012 Chernivtsi, Ukraine.
Oleksii SkorokhodDepartment of Life Sciences and Systems Biology, University of Turin, via Accademia Albertina 13, 10123 Turin, Italy.ORCID 0000-0003-1014-8351
Oksana M VoloshchukEducational and Scientific Institute of Biology, Chemistry and Natural Resources, Yuriy Fedkovych Chernivtsi National University, 58012 Chernivtsi, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver regeneration after partial hepatectomy (PH) is critically influenced by redox balance, which may be severely disrupted under drug-induced liver injury. This study evaluated oxidative stress parameters and inflammatory markers in rats subjected to 70% PH following acetaminophen (APAP)-induced toxicity and assessed the preventive effect of the microalga

Indexed as

acetaminophenC-reactive proteinglutatione peroxidasemicroalgae Desmodesmus armatuspartial hepatectomyreactive oxygen speciesserum alanine aminotransferase (ALT)serum aspartate aminotransferase (AST)superoxide dismutasetoxic liver injury

Identifiers

PMID42072134
PMCPMC13113493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.