Evidence map›Paper›PMID 42072110›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Development of Multi-Bioactive Driven Composite Plant Extracts and Functional Study in Mice and Piglets.

Xin Tao, Yongming Li, Shujie Liu, Wanyun Wu, Jie Wu, Xiaoming Men, Bo Deng, Ziwei Xu

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xin TaoInstitute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Yongming LiInstitute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Shujie LiuInstitute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Wanyun WuInstitute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Jie WuInstitute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Xiaoming MenInstitute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Bo DengInstitute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Ziwei XuInstitute of Animal Husbandry and Veterinary Science, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.

Funding

China Agriculture Research System CARS-35Key Research and Development Program of Zhejiang Province 2024C02004
6 · The paper itself

Abstract

This study aimed to develop a multi-bioactive composite plant extract as an alternative to dietary antibiotics for application in animal production. Five plant materials were initially selected from 23 candidate plants via in vitro antibacterial, antioxidant, and anti-inflammatory screening, and formulated into three candidate extracts (C1, C2, C3) by orthogonal design, with respective dominant activities and moderate the other activities. Three feeding trials in mice demonstrated that administration of 1000 mg/kg C1 or C2 caused no adverse effects on hematological parameters or organ indexes. Supplementation with 250 mg/kg C1 or 125 mg/kg C2 significantly increased body weight gain and feed intake, reduced the feed-to-gain ratio, and modulated gut microbiota composition. In LPS-challenged mice, C1 and C2 restored jejunal villus height and crypt depth, downregulated the gene expression of

Indexed as

antibacterialanti-inflammatoryantioxidantcompositemicepigletsplant extract

Identifiers

PMID42072110
PMCPMC13114034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.