Evidence map›Paper›PMID 42072064›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Melatonin May Improve Post-Thaw Sperm Motility in

Yuxin Zhang, Qingxin Ruan, Weiwei Zhang, Yingxin Wu, Jiajie Li, Qinghua Wang, Fanming Guo, Yang Yang, Zining Meng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuxin ZhangSchool of Life Sciences, State Key Laboratory of Biocontrol/Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/Guangdong Provincial Key Laboratory of Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0009-0002-2889-1178
Qingxin RuanSchool of Life Sciences, State Key Laboratory of Biocontrol/Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/Guangdong Provincial Key Laboratory of Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China.
Weiwei ZhangSchool of Life Sciences, State Key Laboratory of Biocontrol/Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/Guangdong Provincial Key Laboratory of Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China.
Yingxin WuSchool of Life Sciences, State Key Laboratory of Biocontrol/Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/Guangdong Provincial Key Laboratory of Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China.
Jiajie LiSchool of Life Sciences, State Key Laboratory of Biocontrol/Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/Guangdong Provincial Key Laboratory of Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China.
Qinghua WangSchool of Life Sciences, State Key Laboratory of Biocontrol/Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/Guangdong Provincial Key Laboratory of Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China.
Fanming GuoSchool of Life Sciences, State Key Laboratory of Biocontrol/Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/Guangdong Provincial Key Laboratory of Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China.
Yang YangKey Laboratory of Tropical Marine Fish Germplasm Innovation and Utilization, Ministry of Agriculture and Rural Affairs, Hainan Engineering Research Center for Germplasm Innovation and Utilization, Hainan Chenhai Aquatic Co., Ltd., Sanya 570000, China.
Zining MengSchool of Life Sciences, State Key Laboratory of Biocontrol/Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)/Guangdong Provincial Key Laboratory of Aquatic Economic Animals, Sun Yat-sen University, Guangzhou 510275, China.ORCID 0000-0002-5170-9613

Funding

the BIO-KEY Germplasm Preservation Program HT-99982021-0392the Hainan Province "Nan hai xin xing" Science and Technology Innovation Talent Platform Project NHXXRCXM202374the National Natural Science Foundation of China U22A20531the Natural Science Foundation project of Hainan Province 324QY575the Science and Technology Planning Project of Guangdong Province 2023B1212060023the Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) SML2024SP001
6 · The paper itself

Abstract

Melatonin, a well-known antioxidant, has been widely used in sperm cryopreservation of various animals, but its regulatory mechanism in fish remains unclear. This first study on teleosts suggests a potential molecular mechanism by which melatonin may improve post-thaw sperm quality of

Indexed as

Epinephelus fuscoguttatusmelatoninmitochondrial functionMT2 receptorPI3K/Akt/GSK-3β signaling pathwayreactive oxygen speciessperm cryopreservation

Identifiers

PMID42072064
PMCPMC13113446

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.