Evidence map›Paper›PMID 42072029›Full record

ArticleAnimals : an open access journal from MDPI2026

Malic Acid Supplementation on Rumen Fermentation, Nutrient Digestibility, Performance and Carcass Traits in Lambs: A Meta-Analysis and Meta-Regression Considering Dietary Moderators.

Leonardo Tombesi da Rocha, Fernando Skonieski, Tiago Antonio Del Valle, Francine Basso Facco, Paola de Oliveira Selau, Kamily Pech Oliveira, Amanda de Vasconcelos Zucheto, Julio Viégas

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leonardo Tombesi da RochaAnimal Science Department, Federal University of Santa Maria, Avenida Roraima 1000, Santa Maria 97105-900, Brazil.ORCID 0000-0003-2362-7589
Fernando SkonieskiAnimal Science Department, Federal University of Technology-Parana, Estrada Para Boa Esperança km 04, Dois Vizinhos 85660-000, Brazil.
Tiago Antonio Del ValleAnimal Science Department, Federal University of Santa Maria, Avenida Roraima 1000, Santa Maria 97105-900, Brazil.ORCID 0000-0001-8093-7132
Francine Basso FaccoAnimal Science Department, Federal University of Santa Maria, Avenida Roraima 1000, Santa Maria 97105-900, Brazil.ORCID 0000-0001-8182-9766
Paola de Oliveira SelauAnimal Science Department, Federal University of Santa Maria, Avenida Roraima 1000, Santa Maria 97105-900, Brazil.
Kamily Pech OliveiraAnimal Science Department, Federal University of Santa Maria, Avenida Roraima 1000, Santa Maria 97105-900, Brazil.ORCID 0009-0008-6649-9912
Amanda de Vasconcelos ZuchetoAnimal Science Department, Federal University of Santa Maria, Avenida Roraima 1000, Santa Maria 97105-900, Brazil.
Julio ViégasAnimal Science Department, Federal University of Santa Maria, Avenida Roraima 1000, Santa Maria 97105-900, Brazil.ORCID 0000-0003-2169-9570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This meta-analysis and meta-regression evaluated how malic acid supplementation modulates rumen fermentation and its consequences for growth performance, nutrient digestibility, and carcass traits in lambs. Effect sizes (ES) were estimated using a random-effects model. Dietary composition was explored by meta-regression as a key source of heterogeneity, and subgroup analyses were used to compare free malic acid (FMA) and malate. Ruminal pH was not affected by malic acid supplementation. In contrast, total volatile fatty acid concentration increased with malic acid supplementation, particularly in studies using FMA. No effects were detected for propionate concentration, whereas acetate concentration increased (ES = 0.502;

Indexed as

malatemeta-regressionorganic acidsruminal pHvolatile fatty acids

Identifiers

PMID42072029
PMCPMC13113034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.