Trial reportMedicine2026
Effects of temperature management on postoperative myocardial injury in patients undergoing laparoscopic radical resection for colorectal cancer: A randomized controlled trial.
Trial report in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
Abstract
backgroundIntraoperative hypothermia is common in patients undergoing laparoscopic radical resection for colorectal cancer. This study evaluated the effectiveness of maintaining 2 different intraoperative core temperature targets (36°C and 37°C) compared with routine thermal management in reducing postoperative myocardial injury in this patient population.
methodsIn this randomized controlled trial, A total of 144 patients were randomly assigned to 1 of 3 groups: routine (target nasopharyngeal temperature ≥35°C), aggressive (≥36°C), or intensive (37°C) thermal management, utilizing a forced-air warming blanket and warm-water mattress. The primary outcome was postoperative myocardial injury, defined as a cardiac troponin I (cTnI) concentration of 0.04 ng/mL or greater. Secondary outcomes included severe arrhythmia, metabolic acidosis, shivering, and Quality of Recovery-15 (QoR-15) scores.
resultsPostoperative cTnI levels were lower in the aggressive and intensive groups than in the routine group (P <.05). The incidence of myocardial injury was significantly lower in the intensive group than in the routine group (6.5% vs 25.0%; P <.05). The aggressive group had a lower incidence of metabolic acidosis than the routine group (P <.05). The incidence of shivering was lower in both the aggressive and intensive groups than in the routine group (P <.05) and was further reduced in the intensive group compared with that in the aggressive group (P <.05). On postoperative day 1, QoR-15 scores were higher in the aggressive and intensive groups than in the routine group (P <.05), with the intensive group demonstrating a higher score than the aggressive group (P <.05).
conclusionIn patients undergoing laparoscopic radical resection for colorectal cancer, targeting a core intraoperative temperature of 37°C significantly reduces the incidence of postoperative myocardial injury.
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