ArticleMedicine2026
The global trends and hotspots beta-blocker therapy in sepsis and septic shock: A bibliometric analysis based on CiteSpace and VOSviewer.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Research Progress of Sepsis and Nutrition: A Bibliometric and Visualized Analysis.Journal of inflammation research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Beta-blocker therapy has garnered attention for sepsis and septic shock because of its potential benefits in modulating hemodynamics through heart rate control and reducing the in-hospital mortality rate. This study examined the evolving trends and focal points of this domain. This study retrieved 418 articles and reviews related to beta-blocker therapy in sepsis and septic shock published from the Web of Science Core Collection Database from January 1, 1990, to November 30, 2023. CiteSpace and VOSviewer software were used for visual bibliometric analysis, including co-citation analysis of references, co-occurrence analysis of keywords, and collaborative network analysis involving countries/regions, institutions, and authors. Over time, a discernible upward trend has been observed in the annual publication of articles related to β-blockers in sepsis, particularly from 2013 to 2023. Keyword publication burst detection revealed that initial studies primarily focused on the role of excessive catecholamine release as a mechanism and potential therapeutic target in sepsis and septic shock. β-blockers have emerged as a pivotal area of investigation and are associated with improved hemodynamics and decreased in-hospital mortality. The United States is the most prolific contributor, wielding substantial influence, whereas China exhibits a recent surge in publications, ranking second in terms of publication strength. University College London published the most articles, with the University of Oxford demonstrating the highest centrality. Collaborative endeavors are frequently observed among countries and institutions. Beta-blocker therapy may hold promise in reducing in-hospital mortality among patients with sepsis and septic shock, thus becoming a central focus of research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.