ArticleCytopathology : official journal of the British Society for Clinical Cytology2026
On the Prognostic Implications of Nuclear Atypia in Bethesda III Thyroid Nodules.
Article in Cytopathology : official journal of the British Society for Clinical Cytology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Nuclear atypia has been proposed as a useful criterion for subclassifying thyroid nodules with atypia of undetermined significance (AUS), with potential implications for malignancy risk. In our analysis of nodules initially classified as AUS and subsequently confirmed as malignant, clinical outcomes were generally favourable and did not differ according to the presence of nuclear atypia. These findings suggest that while nuclear atypia may have diagnostic relevance, its prognostic impact may be limited.
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