Evidence map›Paper›PMID 42071242›Full record

ArticleJournal of cardiothoracic surgery2026

Dual-chamber epicardial pacing in preterm and low birth weight infants with congenital complete atrioventricular block: a staged approach.

Ahmet Kuddusi İrdem, Yiğit Kılıç, Hasan Balık, Onur Doyurgan

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Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Ahmet Kuddusi İrdemDepartment of Pediatric Cardiac Surgery, Ankara Bilkent City Hospital, Ankara, Turkey. drirdem@gmail.com.
Yiğit KılıçDepartment of Pediatric Cardiac Surgery, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Hasan BalıkDepartment of Pediatric Cardiology, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Onur DoyurganDepartment of Pediatric Cardiac Surgery, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCongenital complete atrioventricular block (CCAVB) in preterm low birth weight neonates poses significant technical challenges for permanent pacemaker implantation. Epicardial pacing is generally preferred in this population; however, definitive implantation in infants weighing < 2500 g may be technically demanding. We evaluated the feasibility and safety of dual-chamber epicardial pacing in preterm low birth weight neonates with autoimmune-associated CCAVB.

methodsEight preterm neonates weighing < 2500 g underwent epicardial pacing between April 2021 and May 2022. All patients initially received temporary epicardial pacing via a subxiphoid approach for rhythm stabilization. Permanent dual-chamber epicardial pacemaker implantation was subsequently performed following clinical optimization and weight gain. Procedural outcomes, pacing performance, ventricular function, and device-related complications were analyzed descriptively.

resultsTemporary pacing was successfully established in all patients at a median postnatal age of 3 days (range, 0-12 days) and a median body weight of 2290 g (range, 1890-2440 g), without major complications. Permanent dual-chamber implantation was achieved in all cases at a median age of 18 days and a mean body weight of 2725 g. Electrical parameters, including sensing amplitudes and capture thresholds, remained stable throughout follow-up. One patient required ventricular lead repositioning due to persistent ventricular dysfunction, with subsequent functional improvement, while ventricular function remained stable or improved in the remaining patients. No device-related complications were observed during the follow-up period. The median follow-up duration was 24 months.

conclusionsThis study indicates that dual-chamber epicardial pacing is feasible and safe in selected preterm low birth weight neonates with CCAVB. When immediate permanent implantation is technically challenging, a staged approach may facilitate stabilization and subsequent definitive implantation with favorable early to short-term outcomes.

Indexed as

Atrioventricular BlockCardiac Pacing, ArtificialInfant, Low Birth WeightPacemaker, ArtificialFeasibility StudiesFemaleHeart BlockHumansInfant, NewbornInfant, PrematureMalePericardiumTreatment OutcomeCongenital complete atrioventricular blockDual-chamber pacingEpicardial pacingLow birth weightPreterm neonateStaged pacemaker implantation

Identifiers

PMID42071242
PMCPMC13312608

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.