Probiotic potential of Lactobacillus acidophilus TMPC 41127 isolated from traditional cheese in inhibiting Salmonella Typhi biofilms and virulence genes.

Behrooz Alizadeh Behbahani, Parisa Ghasemi, Alireza Vasiee, Zeinab Mousavi

Abstract read

In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Probiotic, functional, and safety assessment of Levilactobacillus brevis M3R3 isolated from traditional Khiki cheese.Antonie van Leeuwenhoek · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Behrooz Alizadeh BehbahaniDepartment of Food Science and Technology, Faculty of Animal Science and Food Technology, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Iran. B.alizadeh@asnrukh.ac.ir.

Parisa GhasemiDepartment of Food Science and Technology, Faculty of Animal Science and Food Technology, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Iran.

Alireza VasieeDepartment of Food Safety and Quality Control, Research Institute of Food Science and Technology (RIFST), Mashhad, Iran.

Zeinab MousaviDepartment of Food Science and Technology, Faculty of Animal Science and Food Technology, Agricultural Sciences and Natural Resources University of Khuzestan, Mollasani, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study comprehensively investigated the probiotic and anti-biofilm potential of the Lactobacillus acidophilus TMPC 41127 strain, isolated from traditional Khiki cheese. Initially, its phenotypic characteristics, including resistance to harsh gastrointestinal conditions (low pH and bile salts) and its ability to colonize (surface hydrophobicity 58.9%, auto-aggregation 47.5%, and adhesion to Caco-2 cells 13.9%), were evaluated. The results showed that the cell-free supernatant (CFS) of this strain has strong antimicrobial effects against pathogens, particularly Salmonella enterica subsp. enterica serovar Typhi (Salmonella Typhi). CFS dose-dependently inhibited the formation of Salmonella Typhi biofilms by 79.52% (1/4×MIC) to 13.16% (4×MIC) and degraded mature biofilms, demonstrating anticancer activity against HeLa, HT-29, and MCF-7 cells (IC

Indexed as

BiofilmsCheeseLactobacillus acidophilusProbioticsSalmonella typhiBacterial AdhesionCaco-2 CellsHeLa CellsHT29 CellsHumansVirulenceAnti-biofilmAntimicrobial activityCell-free supernatantProbiotic propertiesSalmonella Typhi

Identifiers

PMID42071076

DOI10.1038/s41598-026-51296-2

PMCPMC13332207

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.