ArticleLasers in surgery and medicine2026
Tissue Micro-Coring Is a Safe and Effective Option for the Treatment of the Nasolabial Fold, Marionette, and Perioral Rhytids.
Article in Lasers in surgery and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundNon-surgical treatment of the aging lower face remains a therapeutic challenge. Tissue Micro-Coring Technology (MCT) is a novel technology that permits the non-surgical removal of skin as micro-cores, tightening skin and inducing collagen and elastin.
objectiveTo evaluate safety and efficacy of MCT for the treatment of the aging lower face.
methodsThis retrospective, single-site study assessed outcomes for subjects treated with MCT. Assessments included the change from baseline in Lemperle Wrinkle Severity Scale (LWSS) assessed for the nasolabial folds (NLF), marionette lines, lip lines, and global esthetic improvement scale (I-GAIS).
resultsA total of 10 patients met the study criteria. Mean (SD) I-GAIS was 1.7 (0.36), and mean (SD) change from baseline in LWSS for NLF, marionette lines, and lip lines were 1.1 (0.46), 1.3 (0.3), and 0.6 (0.35), respectively. Most subjects had some improvement in LWSS across all three treatment areas, with many experiencing > 1-point improvements. LIMITATIONS: Limitations include the retrospective study design, small study population, and single-sex population.
conclusionIn the real-world setting, MCT leads to improvements in global appearance and wrinkle severity. MCT is an effective alternative to injectable fillers for the treatment of nasolabial fold and marionette and perioral lines.
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