ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026
Do non-responders of a geriatric screening questionnaire face lower one-year survival compared to responders? A retrospective cohort study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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- Comments raised by 'Do non-responders to a geriatric screening questionnaire face lower 1-year survival compared to responders? A retrospective cohort study'.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
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10 authors.
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Abstract
purposeA geriatric screening questionnaire was implemented in 2020 at the Department of Oncology, Gødstrup Hospital, Denmark, to identify frailty and individualize cancer care for all patients aged ≥ 60 years. However, not all patients answered. The primary aim of this study was to investigate the association between response status to the geriatric screening questionnaire and one-year survival. A secondary aim was to compare one-year survival according to the responders’ frailty status.
methodsWe conducted a retrospective cohort study including all patients with cancer aged ≥ 60 who were enrolled in the geriatric screening between August 2020 and October 2023. The survival curves for responders and non-responders and across the patients’ frailty status were visualized using Kaplan–Meier plots. The associations were analyzed using logistic regression adjusted for potential confounders.
resultsIn total, 702 patients were included. Among these, 28.1% were non-responders, 46.7% were classified as high risk of frailty, and 25.2% as low risk of frailty. The non-responders had the lowest survival, which declined rapidly in the first 100 days. Survival was similarly lower among non-responders and responders at high risk of frailty, compared to responders at low risk. When adjusted for cohabiting status, age, and cancer type, the odds ratio of survival among non-responders compared to responders was 0.63 (95%CI: 0.42;0.92).
conclusionThe non-responders had the lowest survival, comparable to patients at high risk of frailty among the responders. Their survival declined rapidly suggesting that non-response may signal vulnerability and warrant closer clinical attention or early supportive care.
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