ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026
Dual trajectories of patient-reported fatigue and sleep disturbance in lung cancer survivors.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to quantify the interrelationship between fatigue and sleep disturbance among lung cancer survivors attending traditional Chinese medicine (TCM) rehabilitation clinics.
methodsSymptom burden was assessed through MD Anderson Symptom Inventory-TCM across four time points within two months following the initial visit. A Mixed-effect model was applied to analyze the factors influencing fatigue. The group-based dual trajectory model (GBDTM) was employed to identify the symptom trajectories of fatigue and sleep disturbance and further quantify their interrelationship. Logistic regression models were used to determine the factors associated with different trajectories.
results239 lung cancer survivors were included in this study with sleep disturbance and fatigue reported as the most severe symptoms. The severity of sleep disturbance was positively correlated with that of fatigue. Three distinct trajectories for fatigue have been identified: Low (27%), moderate (55%), and high (18%). Patients with low level sleep disturbance were most likely to be members in the low-to-moderate fatigue group (96.5%), while patients with high level sleep disturbance were most likely to be members in the moderate-to-high fatigue group (93.7%). Notably, patients experiencing high level sleep disturbance had a nearly tenfold increase in the probability of experiencing high level fatigue. Patients with higher BMI (≥ 24) were less likely to be in the high fatigue group, while those with higher ECOG-PS (≥ 1) were more likely to belong to this group.
conclusionHigh level sleep disturbance exacerbated fatigue among lung cancer survivors. BMI and ECOG-PS score had predictive value in fatigue severity.
Indexed as
Identifiers
42070181What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.