ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026
Potential of ASCOT-Carer for evaluating the quality of life of family caregivers for patients with Alzheimer's disease in Japan.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeWe explored the suitability of the Adult Social Care Outcomes Toolkit for Carers (ASCOT-Carer) against the widely used EQ-5D for evaluating the quality of life (QoL) of Japanese caregivers of patients with Alzheimer’s disease. This research aimed to expand the available preference-based measures for assessing caregiver QoL in health economic evaluations in Japan.
methodsThis was a cross-sectional survey using a web-based questionnaire. The alignment between the ASCOT-Carer and established measures, as well as its construct alignment, were evaluated. These were respectively investigated through Pearson’s correlation analysis with the EQ-5D-5L and factor analysis using the EQ-5D-5L and the eight-item short Japanese version of the Zarit Burden Interview (J_ZBI-8).
resultsIn total, 705 live-in family caregivers of patients with Alzheimer’s disease completed the main survey. The absolute correlation coefficients were between J_ZBI-8 and EQ-5D-5L scores, + 0.268; between J_ZBI-8 and ASCOT-Carer scores, + 0.472; and between EQ-5D-5L and ASCOT-Carer scores, + 0.463. Factor analysis revealed that the only factors showing moderate/stronger correlations with factors constituted by J_ZBI-8 were those derived from ASCOT-Carer (inter-factor correlation: +0.31 and + 0.50). The ASCOT-Carer was a more important variable relative to the EQ-5D-5L for measuring caregivers’ QoL related to caregiver burden.
conclusionThe ASCOT-Carer may be a more suitable tool for evaluating the impact of caregiving burden on caregivers’ QoL. When incorporating QoL based on caregiver burden in health economic evaluations, the ASCOT-Carer may be an appropriate option.
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