Evidence map›Paper›PMID 42070050›Full record

ArticleBMC microbiology2026

Genomic and transcriptomic analysis reveals chitin metabolic pathways in the marine bacterium Microbulbifer harenosus CGMCC 1.13584

Xuebing Ren, Xin Song, Hang Zhang, Guangqiang Wang, Fan Xie, Haerlihashi Muhetaerhan, Lianzhong Ai, Yanjun Tian

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Xuebing RenSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Xin SongSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Hang ZhangSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Guangqiang WangSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Fan XieSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200093, China.
Haerlihashi MuhetaerhanSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China.
Lianzhong AiSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, 200093, China.
Yanjun TianSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, 200093, China. tianyj16@163.com.

Funding

Shanghai Rising-Star Program, China 23QA1407000
6 · The paper itself

Abstract

backgroundChitin is the second most abundant polysaccharide in nature, and its degradation by marine microorganisms plays a critical role in the global carbon and nitrogen cycles. This study investigated the marine bacterium Microbulbifer harenosus CGMCC 1.13584

resultsWhen cultured with chitin as the carbon source, the strain exhibited an extended lag phase and enhanced extracellular chitinase activity. Genome sequencing revealed the presence of genes involved in both hydrolytic and oxidative chitin degradation pathways. Transcriptomic analysis showed that genes associated with the hydrolytic pathway were significantly upregulated upon chitin induction. In contrast, within the oxidative degradation pathway, only early-stage response genes (such as those encoding LPMOs) were markedly upregulated, while genes involved in subsequent metabolic steps (converting GlcNAc1A to KDG-6-P) did not show significant upregulation. Furthermore, a gene encoding a GH10 domain-containing protein was found to be substantially upregulated during growth on chitin.

conclusionThese findings indicate that Microbulbifer harenosus CGMCC 1.13584

Indexed as

AlteromonadaceaeChitinGene Expression ProfilingMetabolic Networks and PathwaysBacterial ProteinsCarbonChitinasesGene Expression Regulation, BacterialGenome, BacterialGenomicsTranscriptomeBacterial ProteinsCarbonChitinChitinasesChitinaseChitin metabolic pathwaysGenomic analysisMicrobulbifer harenosusTranscriptomic analysis

Identifiers

PMID42070050
PMCPMC13281251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.