Evidence map›Paper›PMID 42069899›Full record

ArticleScientific reports2026

Segmentation of spinal rootlets across MRI contrasts with RootletSeg.

Kateřina Krejčí, Jiří Chmelík, Sandrine Bédard, Falk Eippert, Ulrike Horn, Virginie Callot, Julien Cohen-Adad, Jan Valošek

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Spatial distribution of spinal cord fMRI activity with electrocutaneous stimulation.medRxiv : the preprint server for health sciences · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kateřina KrejčíDepartment of Biomedical Engineering, FEEC, Brno University of Technology, Brno, Czechia.
Jiří ChmelíkDepartment of Biomedical Engineering, FEEC, Brno University of Technology, Brno, Czechia.
Sandrine BédardNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.
Falk EippertMax Planck Research Group Pain Perception, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Ulrike HornMax Planck Research Group Pain Perception, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Virginie CallotAix Marseille Univ, CNRS, CRMBM, Marseille, France.
Julien Cohen-AdadNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada.
Jan ValošekNeuroPoly Lab, Institute of Biomedical Engineering, Polytechnique Montreal, Montreal, QC, Canada. jan.valosek@upol.cz.

Funding

Canada Foundation for Innovation 32454, 34824Canada Research Chair in Quantitative Magnetic Resonance Imaging CRC-2020-00179Canadian Institute of Health Research PJT-190258, PJT-203803e-INFRA CZ project ID:90254European Research Council (under the European Union's Horizon 2020 research and innovation programme) 758974European Union's Horizon Europe research and innovation programme under the Marie Skłodowska-Curie grant agreement 101107932Fonds de Recherche du Québec - Santé 322736, 324636Ministerstvo Zdravotnictví Ceské Republiky NU22-04-00024Natural Sciences and Engineering Research Council of Canada RGPIN-2019-07244Quebec BioImaging Network 5886, 35450
6 · The paper itself

Abstract

Segmentation of spinal nerve rootlets is relevant for spinal level estimation, lesion classification, neuromodulation therapy, and group-level analyses. The aim of this study was to develop a deep learning method for the automatic segmentation of C2-T1 dorsal and ventral spinal nerve rootlets on various MRI scans. The study included MRI scans from two open-access and one private dataset, consisting of 3D isotropic 3T turbo spin echo T2-weighted (T2w) and 7T MP2RAGE (T1-weighted [T1w] INV1 and INV2, and UNIT1) MRI scans. A deep learning model, RootletSeg, was developed on 93 MRI scans from 50 healthy adults (mean age, 28.70 years ± 6.53 [SD]; 28 [56%] males, 22 [44%] females) and achieved a mean ± SD Dice score of 0.67 ± 0.09 for T1w-INV2, 0.65 ± 0.11 for UNIT1, 0.64 ± 0.08 for T2w, and 0.62 ± 0.10 for T1w-INV1 contrasts. RootletSeg accurately segmented C2-T1 spinal rootlets across MRI contrasts, enabling the determination of spinal levels directly from MRI scans. The method is open-source and can be used for a variety of downstream analyses.

Indexed as

Deep LearningImage Processing, Computer-AssistedMagnetic Resonance ImagingSpinal Nerve RootsAdultFemaleHumansMaleDeep learningNerve rootletsSegmentationSpinal cordSpinal levels

Identifiers

PMID42069899
PMCPMC13332155

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.