Evidence map›Paper›PMID 42069695›Full record

ArticleActa epileptologica2026

Case report: precise mapping and epilepsy surgery of the Broca's area after a comprehensive OPM-MEG investigation of Broca's area localization.

Yuanfeng Zhou, Yanjiong Zhang, Luo Tian, Tianshuang Wang, Min Wang, Renqing Zhu, Hao Li, Zhongwei Qiao, Zhigang Cao, Yuming Peng and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta epileptologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuanfeng Zhou *Department of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Yanjiong Zhang *Department of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Luo TianDepartment of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Tianshuang WangDepartment of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Min WangDepartment of Neurosurgery, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Renqing ZhuDepartment of Neurosurgery, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Hao LiDepartment of Neurosurgery, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Zhongwei QiaoDepartment of Radiology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China.
Zhigang CaoMedical Strategic Alliance, Fosun MedTech, Shanghai, 200000, China.
Yuming PengSchool of Instrumentation Science and Opto-Electronics Engineering, Beihang University, Beijing, 100191, China.
Ming DingSchool of Instrumentation Science and Opto-Electronics Engineering, Beihang University, Beijing, 100191, China. mingding@buaa.edu.cn.
Yi WangDepartment of Neurology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, 201102, China. yiwang@shmu.edu.cn.ORCID http://orcid.org/0000-0002-7051-3739

Funding

Children's Hospital of Fudan University Grant No. EKYX202422Shanghai Municipal Hospital Development Center Grant No. SHDC22022304Shanghai Municipal Science and Technology Major Project Grant No. 2023SHZDZX02
6 · The paper itself

Abstract

backgroundOptically pumped magnetometers magnetoencephalography (OPM-MEG) have demonstrated their value in the diagnosis and mapping of epilepsy, as well as their advantages in pediatric applications. CASE PRESENTATION: We present a case of 8-year-old boy with drug-resistant epilepsy, whose epileptogenic lesion is in left Broca's region. The boy underwent language function evaluation and localization by on-scalp OPM-MEG before surgery. Dipole clusters and Dipole Density of epileptogenic signals by OPM-MEG were located in the left inferior frontal gyrus, though language verbal generation mapping of OPM-MEG signals were mainly located in left frontal orbital gyrus, indicating a localization of the language function area. Seizure freedom and no loss of language function were achieved after MRI-guided laser interstitial thermal therapy.

conclusionsThis article underscores the feasibility of using OPM-MEG to record abnormal discharges of seizure and assess language function area in children, especially in drug-resistant epilepsy surgery involving brain functional areas.

Indexed as

Broca's regionDrug-resistant epilepsyLocalizationOPM-MEG

Identifiers

PMID42069695
PMCPMC13135701

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