ArticleGenome biology2026
Jointly-hic: joint decomposition of contact frequency maps captures salient features of genome architecture across tissues and development.
Article in Genome biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Stepwise reorganization of chromosome conformation and nuclear organization during stem cell differentiation.bioRxiv : the preprint server for biology · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
Chromosome conformation capture methods, such as Hi-C, have been used to profile chromosome organization from a wide variety of biosamples and conditions; however, existing methods for analyzing such datasets have disadvantages for large-scale integrative studies of long-range interactions. To address this shortcoming, we introduce an analytical framework, jointly-hic, that computes harmonized projections across arbitrarily many contact frequency matrices, suitable for integrative studies of compartmentalization and long-range interactions. Our approach produces robust and directly comparable first and higher-order principal component scores that collectively capture biologically meaningful information beyond traditional A/B compartment scores.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.