ArticleNature communications2026
Mild-Sunlight-Activated Safe Photodynamic Therapy Using On-Off Polymer Photosensitizers in Wearable Microneedle Patch.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Photodynamic therapy (PDT) is promising but limited by its dependence on specialized photosources, clinic-based administration, and prolonged post-treatment light avoidance due to phototoxicity side effects. Here, we report mild-sunlight-activated PDT (SunPDT) microneedle patches incorporating polymeric photosensitizers with an intrinsic "on-off" reactive oxygen species (ROS)-generating mechanism, enabling bio-safe, deep-tissue, and self-administered PDT without fixed clinic visits and strictly prolonged light avoidance post-treatment. Rationally designed photosensitizers generate robust ROS under low-intensity mild sunlight (12 mW cm
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