Evidence map›Paper›PMID 42069644›Full record

ReviewBMC biology2026

Plasma membrane invaginations and their diverse cellular functions.

Hongxian Zhu, Carina Lyons, Andrew M Sydor, Donald W Hilgemann, John H Brumell

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hongxian ZhuCell & Systems Biology Program, Hospital for Sick Children, Toronto, ON, M5G 0A4, Canada.
Carina LyonsCell & Systems Biology Program, Hospital for Sick Children, Toronto, ON, M5G 0A4, Canada.
Andrew M SydorCell & Systems Biology Program, Hospital for Sick Children, Toronto, ON, M5G 0A4, Canada.
Donald W HilgemannDepartment of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
John H BrumellCell & Systems Biology Program, Hospital for Sick Children, Toronto, ON, M5G 0A4, Canada. john.brumell@sickkids.ca.

Funding

CIHR PJT #195873Natural Sciences and Engineering Research Council of Canada Discovery Grant
6 · The paper itself

Abstract

The plasma membrane (PM), a dynamic boundary between a cell and its environment, has a complex inner architecture that includes diverse subcellular structures. Among these, PM invaginations (membrane infolds) exhibit varied morphologies and functions. This review explores the structural diversity and physiological roles of PM invaginations, emphasizing their importance in regulating cellular processes in complex organisms. We describe their presence and significance in diverse cell types and organisms. Understanding these specialized structures offers deeper insight into cellular organization and function, highlighting their indispensable role in sustaining biological activity.

Indexed as

Cell MembraneAnimalsHumansFundamental structurePlasma membraneSubcellular structures

Identifiers

PMID42069644
PMCPMC13312728

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.