Evidence map›Paper›PMID 42068490›Full record

ArticleJournal of cancer survivorship : research and practice2026

Neighborhood geographic disparities in colorectal, prostate, breast, and lung cancer risk in Alabama.

R Blake Buchalter, Nashira I Brown, Mahak Bhargava, Hayden D Reeves, Syed M Qasim Hussaini, Timiya S Nolan, Ritu Aneja, Mackenzie E Fowler

Erratum issuedAbstract read
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

R Blake BuchalterDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA. buchalter@uab.edu.
Nashira I BrownO'Neal Comprehensive Cancer Center, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Mahak BhargavaO'Neal Comprehensive Cancer Center, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Hayden D ReevesDivision of Hematology & Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Syed M Qasim HussainiO'Neal Comprehensive Cancer Center, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Timiya S NolanO'Neal Comprehensive Cancer Center, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Ritu AnejaO'Neal Comprehensive Cancer Center, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Mackenzie E FowlerDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

HSET as a racial disparity biomarker for TNBC patientsR01CA239120 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANEJA, RITU · 2019 to 2024
$3.0M
NCI NIH HHS R01 CA239120NCI NIH HHS R01CA239120
6 · The paper itself

Abstract

purposeIncidence of common cancers has been rising in the U.S., with strong geographic variation in risk factors and incidence, particularly in the Southeast and in rural and high-poverty areas. Elevated cancer risk may translate into higher geographic concentrations of cancer survivors who require surveillance, follow-up care, and supportive services. Local geospatial assessment of cancer burden may inform both cancer prevention and survivorship planning.

methodsWe utilized adult (≥ 18 years) incident cases of colorectal, prostate, breast, and lung cancers from the 2010-2019 Alabama Statewide Cancer Registry data. We performed Bayesian disease mapping to estimate census tract-level relative risks (RRs) and classified tracts as hot and cold spots at 99% credible intervals (CrIs). Stratified analyses examined median RR differences by 2010 Rural-Urban Commuting Area codes and 2010-2019 Area Deprivation Index (ADI) quartiles.

resultsWe identified 7, 9, 3, and 83 hot-spot tracts for colorectal, prostate, breast, and lung cancer incidence, respectively. Colorectal hot spots were concentrated in rural southwestern Alabama; prostate cancer hot spots formed a band across south-central Alabama; breast cancer hot spots were localized to Huntsville and Birmingham; and lung cancer hot spots were widespread across rural areas. Increasing rurality was associated with higher median RRs for colorectal, prostate, and lung cancers. CONCLUSIONS & IMPLICATIONS FOR CANCER SURVIVORS: Neighborhood-level geographic disparities in cancer risk highlight areas with higher concentrations of cancer survivors with survivorship care needs. Linking geospatial incidence patterns with survivorship planning could support targeted strategies for surveillance, symptom management, psychosocial care, and health maintenance in high risk communities in the Deep South.

Indexed as

Area Deprivation IndexCancer riskGeographic disparitiesHot spotsRural cancer disparities

Identifiers

PMID42068490
PMCPMC13230096

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.