Evidence map›Paper›PMID 42068370›Full record

ReviewTransgenic research2026

Research progress on the regulatory mechanisms of the PSY promoter.

Bing-Bing He, Xing-Wen Zhou, Jing-Jing Li, Jie Sun, Yi-Qing Xie, Guo-Yong Han, Jia-Shi Lu

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In one paragraph

Review in Transgenic research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bing-Bing HeCollege of Landscape Architecture and Art, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
Xing-Wen ZhouCollege of Architecture and Planning, Fujian University of Technology, Fuzhou, 350118, China. xingwenzhou2003@163.com.
Jing-Jing LiCollege of Architecture and Planning, Fujian University of Technology, Fuzhou, 350118, China.
Jie SunFuzhou Beifeng Forest Farm, Fuzhou Botanical Garden, Fuzhou, 350012, Fujian, China.
Yi-Qing XieInstitute of Economic Forestry, Fujian Academy of Forestry, Fuzhou, 350012, China.
Guo-Yong HanInstitute of Economic Forestry, Fujian Academy of Forestry, Fuzhou, 350012, China.
Jia-Shi LuFlower Research Institute of Guangxi Academy of Agricultural Sciences, Nanning, 530007, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carotenoids are essential pigments in the plant photosynthetic apparatus, functioning in light harvesting, photoprotection, and signal transduction, and serving as precursors of vital nutrients such as vitamin A. Phytoene synthase (PSY) is the first rate-limiting enzyme in the plant carotenoid biosynthetic pathway, and its transcriptional regulation primarily depends on cis-acting promoter elements, associated transcription factors, and epigenetic status. The PSY promoter region contains core cis-elements as well as multiple light-, hormone-, and stress-responsive elements, which collectively function as key regulatory sites governing spatiotemporal expression. This review systematically summarizes recent advances in PSY promoter regulation by plant hormones (e.g., abscisic acid, ethylene, jasmonic acid), environmental factors (light signaling, temperature, salinity, and drought), and epigenetic mechanisms (DNA methylation, histone modifications, and chromatin remodeling). In addition, the application of transgenic and biotechnological approaches to PSY promoter regulation is further summarized. Including promoter sequence engineering with precise editing of cis-elements and promoter-targeted CRISPR activation/interference (CRISPRa/i) for tunable transcriptional control. Emphasis is placed on how these signals are integrated at the promoter level. Deeper insights into these mechanisms will provide both theoretical foundations and practical strategies for enhancing carotenoid accumulation and stress tolerance in crops through molecular design.

Indexed as

Gene Expression Regulation, PlantGeranylgeranyl-Diphosphate GeranylgeranyltransferasePlant ProteinsPlants, Genetically ModifiedPromoter Regions, GeneticCarotenoidsEpigenesis, GeneticPlant Growth RegulatorsCarotenoidsGeranylgeranyl-Diphosphate GeranylgeranyltransferasePlant Growth RegulatorsPlant ProteinsCarotenoidsPromoterPSY geneRegulatory mechanisms

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.