Evidence map›Paper›PMID 42068352›Full record

ArticleVirchows Archiv : an international journal of pathology2026

A primary subcutaneous sarcoma with ATXN1::DUX4 fusion: the first report in soft tissue and further evidence for a CIC/ATXN1 pathway-altered sarcoma family.

Danting Xiong, Xiaona Yin, Rong Fang, Wenjuan Gan, Jiayun Xu, Ming Zhao

Abstract read
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In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danting XiongDepartment of Pathology, the Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China.
Xiaona YinNingbo Clinical Pathology Diagnosis Center, #685 Huancheng North Road, Ningbo, 315000, Zhejiang, China.
Rong FangNingbo Clinical Pathology Diagnosis Center, #685 Huancheng North Road, Ningbo, 315000, Zhejiang, China.
Wenjuan GanDepartment of Pathology, the Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China.
Jiayun XuNingbo Clinical Pathology Diagnosis Center, #685 Huancheng North Road, Ningbo, 315000, Zhejiang, China.
Ming ZhaoNingbo Clinical Pathology Diagnosis Center, #685 Huancheng North Road, Ningbo, 315000, Zhejiang, China. zhaomingpathol@163.com.ORCID http://orcid.org/0000-0001-5971-7303

Funding

Ningbo Municipal Key Medical Discipline (Western Medicine) Development Project 2026-A40Ningbo Top Medical and Health Research Program 2023010211Wu Jieping Medical Foundation Scientific Research Grant 320.6750.2025-24-2Zhejiang Provincial Medicine and Health Research Foundation WKJ-ZJ-26087
6 · The paper itself

Abstract

We present a case of a primary subcutaneous sarcoma harboring an ATXN1::DUX4 gene fusion in a 52-year-old female, representing to our knowledge the first documented occurrence of this molecular subtype arising in soft tissue. The tumor presented as a painless back mass, clinically mimicking a lipoma. Histologic examination revealed an aggressive neoplasm with round to epithelioid morphology, high mitotic activity (30/2 mm

Indexed as

ATXN1AXH domainCIC-rearranged sarcomaDUX4Gene fusionMolecular pathologySoft tissue sarcoma

Identifiers

PMID42068352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.