ArticleJACC. Case reports2026
Simultaneous Closure of Left Atrial Appendage and Mitral Paravalvular Leak.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Two Birds, One Stone: Simultaneous LAA Occlusion and Lateral Mitral PVL Closure.JACC. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn 81-year-old man with 2 prior mitral valve replacements developed recurrent symptomatic paravalvular leak (PVL) despite prior transcatheter closure with vascular plugs. He had ongoing heart failure hospitalizations and hemolytic anemia that limited uninterrupted anticoagulation in the setting of atrial fibrillation and high thromboembolic risk. CASE SUMMARY: The patient underwent a combined procedure with redo PVL closure and left atrial appendage occlusion. Given close anatomic proximity of the lateral PVL to the appendage ostium, a Watchman FLX Pro device was deployed to achieve both left atrial appendage occlusion and sealing of the lateral PVL. Postprocedure, mitral PVL resolved, hemolysis improved at 1-month follow-up, and PVL closure was durable on 3-month follow-up transesophageal echocardiography. DISCUSSION: To our knowledge, this is the first report of Watchman device use for mitral PVL closure. In high-surgical risk patients with atrial fibrillation and bleeding limitations, this single-device strategy may simplify treatment and reduce the need for additional interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.