ArticlePacing and clinical electrophysiology : PACE2026
The Value of Inter-Lesion Time in Linear Lesion Formation Across Varying Catheter Angles and Inter-Lesion Distances.
Article in Pacing and clinical electrophysiology : PACE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- The impact of operator experience on the recurrence rate for atrial fibrillation patients after radiofrequency ablation.Pakistan journal of medical sciences · 2026Article
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12 authors.
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Abstract
backgroundOur previous ex-vivo study showed that shorter inter-lesion time (ILT), defined as the interval between consecutive ablations, enhances lesion depth and may reduce residual conduction during linear ablation. Its impact under practical scenarios, such as parallel catheter orientation and shorter inter-lesion distance (ILD), remains unclear. To investigate how ILT, catheter orientation, and ILD affect lesion depth during linear ablation using high-power (HP) and very-high-power short-duration (vHPSD) settings in an ex-vivo model.
methodsLinear lesions (six per line) were created using the QDOT MICRO catheter (Biosense Webster). Phase 1 evaluated catheter orientation (parallel vs. perpendicular), and Phase 2 compared ILDs (6 mm vs. 4 mm). Minimum perpendicular inter-lesion depths and maximum lesion depths were measured under short ILT (15 s) or long ILT (60 s) using vHPSD (90 W/4 s) or HP (50 W, Ablation Index 350).
resultsShort ILT consistently increased maximum and inter-lesion depths across all settings. In Phase 1, parallel orientation produced deeper lesions than perpendicular under HP, whereas under vHPSD, parallel orientation generated shallower lesions. In Phase 2, lesions at ILD 4 mm were deeper than at 6 mm for the same ILT. Notably, short ILT at ILD6 mm achieved inter-lesion depths comparable to long ILT at ILD4 mm, suggesting an additive benefit of ILT shortening, though it cannot replace a short ILD.
conclusionIn this proof of concept study, shorter ILTs enhanced lesion depth across all conditions. The effect of catheter orientation varied between HP and vHPSD, suggesting that the optimal strategy to maximize ILT effectiveness depends on ablation setting.
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