ArticleAnimal genetics2026
Influence of MC1R Gene Variants on Coat Color of Indicine Cattle Breeds.
Article in Animal genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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13 authors.
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Abstract
Indicine cattle display a broad range of coat colors, representing a relevant and breed-defining trait required for registration in breeder association. Among the genes involved in pigmentation, MC1R stands out for modulating the synthesis of melanin-related proteins and remains poorly explored in indicine cattle breeds. Therefore, we aimed to perform fine mapping of the MC1R gene and to evaluate the association between its polymorphisms and coat color as well as skin pigmentation in seven zebu cattle breeds. A total of 295 individuals belonging to Gir, Nelore, Sindi, Indubrasil, Tabapuã, Guzerá, and Brahman cattle breeds were genotyped through PCR-sequencing, followed by estimates of genotypic and allelic frequencies, linkage disequilibrium, and association with phenotypes using the Kruskal-Wallis test. We identified nine polymorphisms: six non-synonymous SNPs, one coding indel, one synonymous SNP, and one 3' downstream SNP. We report, for the first time, the SNP c.274G>A (p.Val92Met), here designated E
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