ArticleMovement disorders clinical practice2026
Socio-Occupational Functioning after Subthalamic Deep Brain Stimulation in Parkinson's Disease.
Article in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSocio-occupational functioning in patients with Parkinson's disease (PD) treated with subthalamic nucleus deep brain stimulation (STN-DBS) is not fully captured by standard motor and quality-of-life scales.
objectivesTo characterize patient-reported socio-occupational functioning after STN-DBS and explore associated clinical and demographic factors.
methodsThirty-four PD patients were assessed 9-18 months postoperatively using a semi-structured interview covering socio-occupational domains. A composite mean score (Q_mean) was computed as a descriptive index, with clinical associations explored using univariate screening and multivariate linear regression.
resultsThe Q_mean score following STN-DBS was 7.66 ± 0.86 (range 6.00-9.57). In exploratory multivariate analysis, female sex (n = 7) was associated with higher functioning (P = 0.003), whereas GBA variants (n = 5) with lower functioning (P = 0.007). DISCUSSION: Perceived socio-occupational functioning was overall satisfactory at postoperative assessment, with limited association with conventional motor/neuropsychiatric measures, and greater association with individual factors such as sex and genetic background. These exploratory findings support inclusion of socio-occupational perspectives in DBS outcome evaluation.
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